cis-1-(2-Chloroethyl)-3-(3-hydroxycyclohexyl)-1-nitrosourea

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Names

[ CAS No. ]:
56323-45-6

[ Name ]:
cis-1-(2-Chloroethyl)-3-(3-hydroxycyclohexyl)-1-nitrosourea

[Synonym ]:
cis-3-OH CCNU
cis-3-Hydroxy CCNU

Chemical & Physical Properties

[ Density]:
1.46g/cm3

[ Molecular Formula ]:
C9H16ClN3O3

[ Molecular Weight ]:
249.69500

[ Exact Mass ]:
249.08800

[ PSA ]:
82.00000

[ LogP ]:
1.61260

[ Index of Refraction ]:
1.605

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YS4982850
CHEMICAL NAME :
Urea, 1-(2-chloroethyl)-3-(3-hydroxycyclohexyl)-1-nitroso-, (Z)-
CAS REGISTRY NUMBER :
56323-45-6
LAST UPDATED :
198609
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C9-H16-Cl-N3-O3
MOLECULAR WEIGHT :
249.73
WISWESSER LINE NOTATION :
L6TJ AQ CMVNNO&2G -C

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD10 - Lethal Dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,1095,1980

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1-(Piperidin-1-ylmethyl)cyclohexan-1-ol
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(2,6-dimethylphenyl)pyrrolidine-3-carboxamide
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine