6-Chloro 2-oxindole

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Names

[ CAS No. ]:
56341-37-8

[ Name ]:
6-Chloro 2-oxindole

[Synonym ]:
6-chloro-2-oxo-1,2-dihydro-indole
6-Chloro-1,3-dihydro-2H-indol-2-one
6-Chloro 2-oxindole
6-CHLORO-2-OXOINDOLINE
MFCD00209962
6-Chloro-2-oxoindole
2H-Indol-2-one, 6-chloro-1,3-dihydro-
6-chloro-oxindole
6-chloroindolin-2-one
6-CHLORO-2-INDOLINONE
6-CHLORO-2-OXINDOLE

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
329.0±42.0 °C at 760 mmHg

[ Melting Point ]:
195-199 °C(lit.)

[ Molecular Formula ]:
C8H6ClNO

[ Molecular Weight ]:
167.592

[ Flash Point ]:
152.8±27.9 °C

[ Exact Mass ]:
167.013794

[ PSA ]:
29.10000

[ LogP ]:
2.16

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.602

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H317

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22;R43

[ Safety Phrases ]:
S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933790090

Synthetic Route

Precursor & DownStream

Precursor

  • 6-Chloroisatin
  • Dimethyl 2-(4-chloro-2-nitrophenyl)malonate
  • 4-Chloro-2-nitrophenylacetic acid
  • Methyl 2-(4-chloro-2-nitrophenyl)acetate
  • 1,4-Dichloro-2-nitrobenzene
  • (4-Chlor-2-nitro-phenyl)-malonsaeure-diaethylester
  • 6-Chlor-3-hydrazono-2-oxo-indolin
  • 3-Chloroaniline
  • N-(3-CHLORO-PHENYL)-2-[(E)-HYDROXYIMINO]-ACETAMIDE

DownStream

  • 6-pyridin-3-yl-1,3-dihydroindol-2-one
  • 6-Chloroisatin
  • Ziprasidone HCl
  • 6-Chloro-5-(2-chloroethyl)oxindole
  • 2H-Indol-2-one, 6-chloro-5-(2-chloro-1-hydroxyethyl)-1,3-dihydro
  • 5-Chloroacetyl-6-chloro-1,3-dihydro-2H-indole-2-one
  • (2-Amino-4-chlorophenyl)acetic acid
  • 1-acetyl-6-chloro-3H-indol-2-one
  • 2,6-dichloro-1H-indole-3-carbaldehyde
  • 6-CHLORO-3-(3-CHLORO-2-FLUOROBENZYLIDENE)INDOLIN-2-ONE

Customs

[ HS Code ]: 2933790090

[ Summary ]:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

Articles

Synthesis and biological evaluation of new pyridone-annelated isoindigos as anti-proliferative agents.

Molecules 19(9) , 13076-92, (2014)

A selected set of substituted pyridone-annelated isoindigos 3a-f has been synthesized via interaction of 5- and 6-substituted oxindoles 2a-f with 6-ethyl-1,2,9-trioxopyrrolo[3,2-f]quinoline-8-carboxyl...


More Articles


Related Compounds

  • 6-Chloro-7-aza-2-oxindole
  • [6-chloro-2-methyl-4-[(2,2,2-trifluoroacetyl)amino]oxan-3-yl] 4-nitrobenzoate
  • 6-CHLORO-2-IODO-1-METHYL-1H-INDOLE
  • 6-CHLORO-2-METHYLQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
  • 6-Chloro-2,3,4,9-tetrahydro-1H-carbazole
  • 6-Chloro-2,4-dihydroxy-5-methyl-3-nitropyridine
  • Tert-butyl 1-(2-aminoethyl)-8-azaspiro[4.5]decane-8-carboxylate
  • Tert-butyl 6-(2-aminoethyl)-2-azaspiro[4.4]nonane-2-carboxylate
  • 2-{7-Oxaspiro[bicyclo[2.2.1]heptane-2,1'-cyclopentane]-5'-yl}ethan-1-amine
  • 2-{1,1,2,2-Tetramethylspiro[2.4]heptan-4-yl}ethan-1-amine
  • 2-{1,1-Dimethylspiro[2.4]heptan-4-yl}acetic acid
  • benzyl N-[1-(chlorosulfonyl)-4-fluorobutan-2-yl]carbamate
  • 5,9-Dioxa-13-azadispiro[2.2.6^{6}.2^{3}]tetradecane
  • Benzyl 3-[(chlorosulfonyl)methyl]-8-azabicyclo[3.2.1]octane-8-carboxylate
  • 1-[(3S)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pentanoyl]-3-(prop-2-en-1-yl)azetidine-3-carboxylic acid
  • 4-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-methylpentanamido]-1-methyl-1H-pyrazole-5-carboxylic acid
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