5-Fluoro-2-oxindole

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Names

[ CAS No. ]:
56341-41-4

[ Name ]:
5-Fluoro-2-oxindole

[Synonym ]:
5-Fluoro-2-oxindole
5-Fluorooxindole
5-Fluoroindole-2-One
5-FLUROOXINDOLE
T56 BMV DHJ GF
Fluorooxindole
MFCD02179598
5-fluoro-2-oxo-1,2-dihydro-indole
5-Fluoro-1,3-dihydro-2H-indol-2-one
5-Fluoro-1,3-dihydro-indol-2-one
EINECS 446-540-4
5-FLUORO-2-OXYINDOLE
2H-Indol-2-one, 5-fluoro-1,3-dihydro-
5-fluoroindolin-2-one
5-Fluoro-2-indolinone
5-Fluoro-1,3-dihydroindol-2-one

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
307.2±42.0 °C at 760 mmHg

[ Melting Point ]:
143-147 °C(lit.)

[ Molecular Formula ]:
C8H6FNO

[ Molecular Weight ]:
151.14

[ Flash Point ]:
139.6±27.9 °C

[ Exact Mass ]:
151.043335

[ PSA ]:
29.10000

[ LogP ]:
1.54

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.560

[ Storage condition ]:
Keep Cold

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi,C

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5-Fluoroisatin
  • 2-(2-amino-5-fluorophenyl)acetohydrazide
  • 1H-indole-2,3-dione, 5-fluoro-, 3-hydrazone
  • methyl 5-fluoro-2-oxo-1,3-dihydroindole-3-carboxylate
  • (5-FLUORO-2-NITRO-PHENYL)-ACETIC ACID
  • Benzeneacetic acid, 5-fluoro-2-nitro-, Methyl ester
  • 1-hydroxy-3H-indol-2-one
  • Chloroacetyl chloride
  • 4-Fluoroaniline
  • n-(chloroacetyl)-4-fluoroaniline

DownStream

  • 5-[(Z)-(5-Fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4 -dimethyl-1H-pyrrole-3-carboxylic acid
  • Sunitinib
  • Sunitinib malate
  • 5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid
  • Toceranib
  • sunitinib
  • 5-Fluoroisatin
  • 5-Fluoroindoline
  • 1'-BOC-5-FLUORO-1,2-DIHYDRO-2-OXO-SPIRO[3H-INDOLE-3,4'-PIPERIDINE]
  • 5'-Fluorospiro[cyclopropane-1,3'-indolin]-2'-one

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 5-fluoro-2-oxindole
  • 7-Chloro-5-fluoro-2-oxindole
  • 5-Fluoro-2-benzofuran-1(3H)-one
  • 5-Fluoro-2-(2-methoxyethoxy)pyridine
  • 5-Fluoro-2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile
  • 5-FLUORO-2-(4-METHOXYPHENYL)BENZO[D]THIAZOLE