Isoserine

Suppliers

Names

[ CAS No. ]:
565-71-9

[ Name ]:
Isoserine

[Synonym ]:
3-Aminolactic acid
MFCD00008138
5-Oxo-L-proline 1-methylethyl ester
(DL)-3-Amino-2-hydroxypropanoic Acid
L-Pyroglutamic acid isopropyl ester
isopropyl 5-oxo-L-prolinate
3-Amino-2-hydroxypropanoic acid
Isoserine
Propanoic acid, 3-amino-2-hydroxy-
pyroglutamic acid iso-propyl ester
3-Amino-2-hydroxypropionic acid

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
386.6±27.0 °C at 760 mmHg

[ Melting Point ]:
235ºC (dec.)

[ Molecular Formula ]:
C₃H₇NO₃

[ Molecular Weight ]:
105.093

[ Flash Point ]:
187.6±23.7 °C

[ Exact Mass ]:
105.042595

[ PSA ]:
83.55000

[ LogP ]:
-0.97

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.519

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(S)-benzyl 2-oxooxazolidine-5-carboxylate
(2S)-3-{[(benzyloxy)carbonyl]amino}-2-hydroxypropanoic acid
O-[3-amino-(2S)-t-butyldimethylsilyloxypropanoyl]-(1'R,2'S,5'R)-8'phenylmenthol
(+)-ethyl N,O-diacetyl-3-amino-2-hydroxypropionate
O-Acetyl-(S)-isoserine
(S)-3-(1,3-DIOXOISOINDOLIN-2-YL)-2-HYDROXYPROPANOIC ACID
3-Amino-1,2-propanediol
(S)-Oxirane-2-carboxylic acid

DownStream

Articles

Novel parent structures for inhibitors of the murine GABA transporters mGAT3 and mGAT4.

Eur. J. Pharmacol. 519(1-2) , 43-7, (2005)

Searching for potent and subtype selective parent structures of the murine gamma-aminobutyric acid (GABA) transporter subtypes mGAT3 and mGAT4 a series of amino acids was characterised in a uniform [3...

Glycine conjugates in a lepidopteran insect herbivore--the metabolism of benzylglucosinolate in the cabbage white butterfly, Pieris rapae.

ChemBioChem. 7(12) , 1982-9, (2006)

Herbivores have developed a wide array of countermeasures to overcome plants' chemical defences. Larvae of the cabbage white butterfly, Pieris rapae, feed exclusively on plants of the Brassicales orde...

Microbial resolution of 2-hydroxy-3-nitropropionic acid for synthesis of optically active isoserine.

Biosci. Biotechnol. Biochem. 65(5) , 1258-60, (2001)

The biocatalytic stereoselective hydrolysis of 2-hydroxy-3-nitropropionic acid esters was studied. Forty enzymes and three hundred microorganism strains were examined for their ability to hydrolyze et...