2-{[(tert-butoxy)carbonyl]amino}-3-cyclobutylpropanoic acid

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Names

[ CAS No. ]:
565456-75-9

[ Name ]:
2-{[(tert-butoxy)carbonyl]amino}-3-cyclobutylpropanoic acid

[Synonym ]:
(S)-2-(TERT-BUTOXYCARBONYLAMINO)-3-CYCLOBUTYLPROPANOIC ACID
BOC-DL-CYCLOBUTYLALANINE
3-Cyclobutyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}alanine
2-(tert-butoxycarbonylamino)-3-cyclobutylpropanoic acid
(R)-2-(TERT-BUTOXYCARBONYLAMINO)-3-CYCLOBUTYLPROPANOIC ACID
BOC-3-CYCLOBUTYL-DL-ALANINE
Boc-3-Cyclobutylalanine
Cyclobutanepropanoic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-
CYC133

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
391.7±25.0 °C at 760 mmHg

[ Molecular Formula ]:
C12H21NO4

[ Molecular Weight ]:
243.299

[ Flash Point ]:
190.7±23.2 °C

[ Exact Mass ]:
243.147064

[ PSA ]:
79.12000

[ LogP ]:
2.56

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.493

Safety Information

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • ETHYL 2-((TERT-BUTOXYCARBONYL)AMINO)-3-CYCLOBUTYLPROPANOATE
  • Ethyl 3-cyclobutylalaninate
  • Di-tert-butyl dicarbonate
  • Cyclobutylmethyl bromide
  • 2-(benzhydrylidene-amino)-3-cyclobutyl-propionic acid ethyl ester

DownStream

  • TERT-BUTYL (4-AMINO-1-CYCLOBUTYL-3-HYDROXY-4-OXOBUTAN-2-YL)CARBAMATE
  • Boceprevir
  • TERT-BUTYL (1-CYCLOBUTYL-3-OXOPROPAN-2-YL)CARBAMATE
  • TERT-BUTYL (1-CYANO-3-CYCLOBUTYL-1-HYDROXYPROPAN-2-YL)CARBAMATE
  • [1-(Cyclobutylmethyl)-2-(MethoxyMethylamino)-2-oxoethyl]-carbamic Acid 1,1-Dimethylethyl Ester

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%