Coprostanone

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Names

[ CAS No. ]:
566-88-1

[ Name ]:
Coprostanone

[Synonym ]:
5alpha-Cholestanone
5A-Cholestan-3-one
5α-Cholestan-3-one
5a-Cholestanone
5α-Cholestane-3-one
3-Keto-5alpha-cholestane
5alpha-Coprostanone
(5α)-Cholestan-3-one
5alpha-cholestan-3-one
(5S,8R,9S,10S,13R,14S,17R)-10,13-Dimethyl-17-[(2R)-6-methyl-2-heptanyl]hexadecahydro-3H-cyclopenta[a]phenanthren-3-one
Cholestan-3-one, (5α)-
5α-Cholestan-3-one (8CI)
5alpha-Cholestane-3-one
Coprostanone
(5S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
MFCD00065901

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
452.9±13.0 °C at 760 mmHg

[ Melting Point ]:
127-131ºC

[ Molecular Formula ]:
C27H46O

[ Molecular Weight ]:
386.654

[ Flash Point ]:
219.3±12.1 °C

[ Exact Mass ]:
386.354858

[ PSA ]:
17.07000

[ LogP ]:
9.64

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.498

[ Storage condition ]:
-20℃

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Risk Phrases ]:
R24/25

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5α-cholestan-1-en-3-one
  • Dihydrocholesterol
  • Cholest-4-en-3-one
  • Cholestan-3-one, oxime,(5a)-
  • 5β-cholestan-3β-ol
  • 5-CHOLESTEN-3-ONE
  • Phenylhydrazon des 5α-Cholestan-3-on

DownStream

  • Cyclopenta[5,6]naphth[1,2-d]azepin-2 (1H)-one, 8.beta.-(1, 5-dimethylhexyl)-3,4,5,5a,5b.alpha.,6,7,7a,8,9,10,10a.alpha., 10b.beta.,11,12,12a.alpha.-hexadecahydro-5a.beta., 7a.beta.-dimethyl-
  • (5a)-Cholestane
  • 5α-cholest-2-ene
  • Cholest-4-en-3-one
  • Cholesta-1,4-dien-3-one
  • 5α-cholestan-1-en-3-one
  • Epidihydrocholesterin (JAN)
  • Dihydrocholesterol

Articles

In vitro modulation of rat adipocyte ghost membrane fluidity by cholesterol oxysterols.

Experientia 51(7) , 731-7, (1995)

The effects of cholesterol and cholesterol-derived oxysterols (cholestanone, cholestenone, coprostanone and epicoprostanol) on adipocyte ghost membrane fluidity were studied using a fluorescence depol...

Diet, nutrition intake, and metabolism in populations at high and low risk for colon cancer. Metabolism of neutral sterols.

Am. J. Clin. Nutr. 40(4 Suppl) , 931-6, (1984)

Cholesterol and its metabolites, together with bile acids, are implicated as risk factors in the genesis and progression of colon cancer. This study was designed to determine differences in the neutra...

Potentiation of beta-adrenoceptor agonist mediated-lipolysis by cholesterol-derived oxysterols.

Biochem. Mol. Biol. Int. 35(6) , 1349-58, (1995)

Cholesterol-derived oxysterols such as cholestanol, cholestanone and coprostanone were able to potentiate epinephrine-induced lipolysis in intact rat adipocytes but not cholesterol. The relative poten...


More Articles

Related Compounds

  • Coprostanone
  • coprostanone
  • 4-[5-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpentanamido]-2-methylbut-2-enoic acid
  • 4-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylpentanamido]-2-methylbut-2-enoic acid
  • 4-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methoxybutanamido]-2-methylbut-2-enoic acid
  • 4-{[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-1,3-thiazol-4-yl]formamido}-2-methylbut-2-enoic acid
  • Methyl 3-(4-((1,3-dioxoisoindolin-2-yl)methyl)phenyl)acrylate
  • 3-[N-benzyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4,4-dimethylpentanamido]propanoic acid
  • 1-[2-cyclopropyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoyl]-1,2,3,6-tetrahydropyridine-4-carboxylic acid
  • 1-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentanecarbonyl]-1,2,3,6-tetrahydropyridine-4-carboxylic acid
  • 1-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)oxolane-3-carbonyl]-1,2,3,6-tetrahydropyridine-4-carboxylic acid
  • 3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-{[2-(3-methylpyridin-2-yl)ethyl]carbamoyl}propanoic acid
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