2-(Dimethylamino)pyridine

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Names

[ CAS No. ]:
5683-33-0

[ Name ]:
2-(Dimethylamino)pyridine

[Synonym ]:
2-Pyridinamine, N,N-dimethyl-
(Dimethylamino)-2-pyridine
N,N-dimethylpyridin-2-amine
Pyridine, 2- (dimethylamino)-
MFCD00006261
dimethylaminopyridine
2-dimethylaminopyridine
N,N-Dimethyl-2-pyridinamine
EINECS 227-147-5

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
196.0±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C7H10N2

[ Molecular Weight ]:
122.168

[ Flash Point ]:
75.0±0.0 °C

[ Exact Mass ]:
122.084396

[ PSA ]:
16.13000

[ LogP ]:
1.41

[ Vapour Pressure ]:
0.4±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.554

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
US9200000
CHEMICAL NAME :
Pyridine, 2-dimethylamino-
CAS REGISTRY NUMBER :
5683-33-0
BEILSTEIN REFERENCE NO. :
0110353
LAST UPDATED :
199712
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C7-H10-N2
MOLECULAR WEIGHT :
122.19
WISWESSER LINE NOTATION :
T6NJ BN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
182 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 26,345,1968

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S23-S26-S36

[ RIDADR ]:
1993

[ WGK Germany ]:
3

[ RTECS ]:
US9200000

[ Packaging Group ]:
II

[ Hazard Class ]:
3

[ HS Code ]:
29333999

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Aminopyridine
  • Formaldehyde
  • 2-Chloropyridine
  • Dimethylamine
  • 4-Hydroxypyridine
  • diphosphorus pentoxide
  • 2-(Methylamino)pyridine
  • Carbon dioxide
  • 2-Bromopyridine
  • N,N-Dimethylformamide

DownStream

  • N2,N2-dimethylpyridine-2,5-diamine
  • 2-(dimethylamino)-5-nitropyridine
  • N,N-Dimethyl-3-nitropyridin-2-amine
  • N-benzyl-N-methyl-pyridin-2-amine
  • 2-Benzylaminopyridine
  • 2-Benzylamino-5-benzylpyridine
  • 2-Pyridinamine,5,5'-methylenebis[N,N-dimethyl-
  • Pyridine
  • 3-Chloropyridine

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Related Compounds

  • 2-(dimethylamino)pyridine 1-oxide
  • 3-amino-2-(dimethylamino)pyridine
  • 2-(dimethylamino)pyridine-3-carbonitrile
  • 2-(dimethylamino)pyridine-4-carbaldehyde
  • 2-(dimethylamino)pyridine-3-carbaldehyde
  • 2-(dimethylamino)pyridine-4-carbonitrile
  • tert-butyl N-(3-aminopropoxy)-N-[(tert-butoxy)carbonyl]carbamate
  • {1-[4-(Methylamino)pyrimidin-2-YL]piperidin-4-YL}(pyridin-3-YL)methanol
  • tert-butyl N-(2-aminoethoxy)carbamate
  • N-[(1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)methyl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide
  • 3-(2-Oxo-2-phenylethylthio)benzoic acid
  • (2-fluorophenyl)(2-piperidino-4,5-dihydro-1H-imidazol-1-yl)methanone
  • 4-(3-Aminoprop-1-en-1-yl)-2-methoxyphenol
  • N-Methyl-2-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide
  • 1-[4-(5-Bromo-1H-indole-2-carbonyl)piperazin-1-YL]-2-(2-methylphenyl)ethanone
  • 5-Ethyl-2-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-ol
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