1,4-bis(chloromethoxymethyl)benzene

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Names

[ CAS No. ]:
56894-91-8

[ Name ]:
1,4-bis(chloromethoxymethyl)benzene

Chemical & Physical Properties

[ Density]:
1.233g/cm3

[ Boiling Point ]:
307.1ºC at 760 mmHg

[ Molecular Formula ]:
C10H12Cl2O2

[ Molecular Weight ]:
235.10700

[ Flash Point ]:
114.4ºC

[ Exact Mass ]:
234.02100

[ PSA ]:
18.46000

[ LogP ]:
3.11240

[ Index of Refraction ]:
1.526

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CY8420000
CHEMICAL NAME :
Benzene, 1,4-bis(chloromethoxymethyl)-
CAS REGISTRY NUMBER :
56894-91-8
LAST UPDATED :
199510
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C10-H12-Cl2-O2
MOLECULAR WEIGHT :
235.12
WISWESSER LINE NOTATION :
G1O1R D1O1G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2590 mg/kg/72W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,2553,1975
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
310 mg/kg/78W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,2553,1975
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
970 mg/kg/81W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,2553,1975 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,37,1977 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,37,1977 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

Related Compounds

  • 1,4-bis(chloromethoxymethyl)cyclohexane
  • 1,4-bis(ethenoxy)benzene
  • 1,4-BIS(TRICHLOROMETHYL)BENZENE
  • 1,4-bis(ethenylsulfonylmethyl)benzene
  • 1,4-bis(cyclopropylmethoxy)benzene
  • 1,4-bis(dimethoxymethyl)benzene
  • (S)-6-Bromo-3-(sec-butyl)-4-chloro-3H-imidazo[4,5-c]pyridine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • tert-butyl 2-[2-(N-methylprop-2-enamido)acetyl]-1,2-diazinane-1-carboxylate
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1-[1-(3-fluorobenzenesulfonyl)azetidin-3-yl]-2-(propan-2-yl)-1H-1,3-benzodiazole
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 2-(2-Methylpropyl)-7-[1-(prop-2-enoyl)piperidine-4-carbonyl]-octahydroimidazo[1,5-a]pyrazin-3-one
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide