2-[(2-tert-butylphenyl)-phenylmethoxy]ethyl-dimethylazanium,chloride
Names
[ CAS No. ]:
5697-60-9
[ Name ]:
2-[(2-tert-butylphenyl)-phenylmethoxy]ethyl-dimethylazanium,chloride
[Synonym ]:
Ethanamine,2-((2-(1,1-dimethylethyl)phenyl)phenylmethoxy)-N,N-dimethyl-,hydrochloride
2-[(2-tert-butylphenyl)-phenylmethoxy]ethyl-dimethylazanium chloride
BS 6534
Chemical & Physical Properties
[ Molecular Formula ]:
C21H30ClNO
[ Molecular Weight ]:
347.92200
[ Exact Mass ]:
347.20200
[ PSA ]:
12.47000
[ LogP ]:
5.45370
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KQ8560000
- CHEMICAL NAME :
- Ethylamine, 2-((o-tert-butyl-alpha-phenylbenzyl)oxy)-N,N-dimethyl -, hydrochloride
- CAS REGISTRY NUMBER :
- 5697-60-9
- LAST UPDATED :
- 198212
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C21-H29-N-O.Cl-H
- MOLECULAR WEIGHT :
- 347.97
- WISWESSER LINE NOTATION :
- 1X1&1&R BYR&O2N1&1 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - local anesthetic Autonomic Nervous System - smooth muscle relaxant (mechanism undefined, spasmolytic) Vascular - regional or general arteriolar constriction
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 138,62,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 115 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - local anesthetic Autonomic Nervous System - smooth muscle relaxant (mechanism undefined, spasmolytic) Vascular - regional or general arteriolar constriction
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 138,62,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 350 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - local anesthetic Autonomic Nervous System - smooth muscle relaxant (mechanism undefined, spasmolytic) Vascular - regional or general arteriolar constriction
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 138,62,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - local anesthetic Autonomic Nervous System - smooth muscle relaxant (mechanism undefined, spasmolytic) Vascular - regional or general arteriolar constriction
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 138,62,1962