celiprolol

Suppliers

Names

[ Name ]:
celiprolol

[Synonym ]:
3-(3-Acetyl-4-{2-hydroxy-3-[(2-methyl-2-propanyl)amino]propoxy}phenyl)-1,1-diethylurea
3-{3-Acetyl-4-[3-(tert-butylamino)-2-hydroxypropoxy]phenyl}-1,1-diethylurea
CCRIS 3400
Celectol
3-<3-Acetyl-4-(3-tert-butylamino-2-hydroxy-propoxy)-phenyl>-1,1-diethylharnstoff
EINECS 260-497-7
Celiprololum [INN-Latin]
N-[3-acetyl-4-(3'-tert-butylamino-2'-hydroxy)propoxy]-phenyl-N'-diethylurea
Urea, N'-(3-acetyl-4-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)phenyl)-N,N-diethyl-
RHC-5320A
Urea, N'-[3-acetyl-4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]phenyl]-N,N-diethyl-
UL/1677
N-[3-Acetyl-4-(3'-tert-butylamino-2'-hydroxy)propoxy]phenyl-N'-diethylurea
celiprolol
UNII:DRB57K47QC
N'-[3-Acetyl-4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]phenyl]-N,N-diethylurea
N'-(3-acetyl-4-(3-((1,1-dimethylethyl)-amino)-2-hydroxypropoxy)-phenyl)-N,N-diethylurea
MFCD00864577
[14C]-Celiprolol

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
586.5±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₃₃N₃O₄

[ Molecular Weight ]:
379.494

[ Flash Point ]:
308.5±30.1 °C

[ Exact Mass ]:
379.247101

[ PSA ]:
90.90000

[ LogP ]:
1.92

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.545

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YR6555925

CHEMICAL NAME :: Urea, N'-(3-acetyl-4-(3-((1,1-dimethylethyl)amino)-2-hydrox ypropoxy)phenyl)-N,N- diethyl-

CAS REGISTRY NUMBER :: 56980-93-9

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C20-H33-N3-O4

MOLECULAR WEIGHT :: 379.56

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 407 gm/kg/2Y-C

TOXIC EFFECTS :: Behavioral - food intake (animal) Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 6,6,1986

Safety Information

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R36/37/38:Irritating to eyes, respiratory system and skin .

[ Safety Phrases ]:
S26-S36/37/39

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

P-NITROPHENYLACETATE
tert-Butylamine
3-[3-ACETYL-4-(3-BROMO-2-HYDROXYPROPOXY)PHENYL]-1,1-DIETHYLUREA
N'-(3-acetyl-4-hydroxyphenyl)-N,N-diethyl urea
4-Nitrophenol
1-(2-Hydroxy-5-nitrophenyl)ethanone
5-Nitro-2-(oxiranylmethoxy)acetophenone
3-(4-ethoxyphenyl)-1,1-diethylurea
Diethylcarbamic chloride
2-Phenoxyethanamine

DownStream

Related Compounds

d-Celiprolol
celiprolol FD
Celiprolol HCl
(-)-celiprolol
Celiprolol-d9 hydrochloride
(S)-(-)-Celiprolol Hydrochloride
4-(4-Butoxyphenyl)-3-(2-hydroxyphenyl)-5-(2-methoxyethyl)-1,2,3,3a,4,6a-hexahydropyrrolo[3,4-c]pyrazol-6-one
Methyl 4-[5-(3-ethoxypropyl)-3-(2-hydroxyphenyl)-6-oxo-1,2,3,3a,4,6a-hexahydropyrrolo[3,4-c]pyrazol-4-yl]benzoate
(2-Bromo-3-fluorophenyl)methanethiol
4-(4-Butoxyphenyl)-3-(2-hydroxyphenyl)-5-propyl-1,2,3,3a,4,6a-hexahydropyrrolo[3,4-c]pyrazol-6-one
4-(4-Butoxyphenyl)-5-(furan-2-ylmethyl)-3-(2-hydroxyphenyl)-1,2,3,3a,4,6a-hexahydropyrrolo[3,4-c]pyrazol-6-one
4-[4-(1,3-Benzothiazol-2-yl)-5-methylpyrazolidin-3-yl]-6-ethyl-2-[(4-methylpiperazin-1-yl)methyl]benzene-1,3-diol
2-Amino-5-(benzyloxy)-4-methylbenzonitrile
3-[(E)-hydroxy-[1-(2-morpholin-4-ylethyl)-4,5-dioxo-2-phenylpyrrolidin-3-ylidene]methyl]-N,N-dimethylbenzenesulfonamide
3-[(E)-[1-[3-(dimethylamino)propyl]-2-(4-fluorophenyl)-4,5-dioxopyrrolidin-3-ylidene]-hydroxymethyl]-N,N-dimethylbenzenesulfonamide
3-[(E)-[1-[3-(dimethylamino)propyl]-4,5-dioxo-2-phenylpyrrolidin-3-ylidene]-hydroxymethyl]-N,N-dimethylbenzenesulfonamide

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