1-Acetylguanidine

Names

[ Name ]:
1-Acetylguanidine

[Synonym ]:
N-Carbamimidoylacetamide
N-(diaminomethylidene)acetamide
EINECS 227-180-5
Acetamide, N-(aminoiminomethyl)-
MFCD00075615

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
238.7ºC at 760mmHg

[ Melting Point ]:
181-183ºC(lit.)

[ Molecular Formula ]:
C₃H₇N₃O

[ Molecular Weight ]:
101.107

[ Flash Point ]:
98.2ºC

[ Exact Mass ]:
101.058914

[ PSA ]:
78.97000

[ LogP ]:
-1.86

[ Index of Refraction ]:
1.550

MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2925290090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2925290090

[ Summary ]:
2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Novel 1H-imidazol-2-amine derivatives as potent and orally active vascular adhesion protein-1 (VAP-1) inhibitors for diabetic macular edema treatment.

Bioorg. Med. Chem. 21(13) , 3873-81, (2013)

Novel thiazole derivatives were synthesized and evaluated as vascular adhesion protein-1 (VAP-1) inhibitors. Although we previously identified a compound (2) with potent VAP-1 inhibitory activity in r...

Synthesis and biological evaluation of 4(5)-(6-alkylpyridin-2-yl)imidazoles as transforming growth factor-beta type 1 receptor kinase inhibitors.

J. Med. Chem. 50(13) , 3143-7, (2007)

A series of 4(5)-(6-alkylpyridin-2-yl)imidazoles 13a-p, 17a, and 17b have been synthesized and evaluated for ALK5 inhibitory activity in an enzyme assay and in cell-based luciferase reporter assays. T...

One-pot synthesis of N²-aminoprotected 6-substituted and cycloalka[d] 4-trifluoromethyl-2-acetylaminopyrimidines. Bonacorso HG, et al.

J. Heterocycl. Chem. 45(2) , 483-87, (2008)

1-phenyl-3H-[1,2,4]triazolo[4,3-a]quinazolin-5-one
1-[2-(2-fluorobenzoyl)pyrrol-1-yl]propan-2-yl-dimethylazanium,chloride
1-[2-(2-methoxybenzoyl)pyrrol-1-yl]propan-2-yl-dimethylazanium,chloride
1-methyl-3-[3-[[methyl-[(4-nitrophenyl)methyl]carbamoyl]amino]phenyl]-1-[(4-nitrophenyl)methyl]urea
1-(2-methoxyphenyl)-4-(2-phenylethyl)piperazine
1-(3-Chlorophenyl)-4-propylpiperazine
Tert-butyl 6-bromo-1,2,3,5-tetrahydro-4,1-benzoxazepine-1-carboxylate
3-(2-Oxo-1,2-dihydroquinolin-4-yl)-2-(2,2,2-trifluoroacetamido)propanoic acid
Tert-butyl 2-amino-3-(4-bromophenyl)-3-methylbutanoate
benzyl N-(6-chloro-5-cyanopyridin-3-yl)carbamate
tert-butyl N-(2-chloro-3-nitropyridin-4-yl)-N-methylcarbamate
benzyl N-(2-chloro-5-cyanopyridin-3-yl)carbamate
Methyl 6-{[(tert-butoxy)carbonyl]amino}-2-chloropyrimidine-4-carboxylate
Methyl 2-{[(tert-butoxy)carbonyl]amino}-4-chloropyrimidine-5-carboxylate
2,4-Dimethoxy-6-(2,2,2-trifluoroacetamido)benzoic acid
1-methyl-4-{[(prop-2-en-1-yloxy)carbonyl]amino}-3-(trifluoromethyl)-1H-pyrazole-5-carboxylic acid

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