Creatine

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Names

[ CAS No. ]:
57-00-1

[ Name ]:
Creatine

[Synonym ]:
N-AMIDINOSARCOSIN
[[Amino(imino)methyl](methyl)amino]acetic acid
Glycine, N-(aminoiminomethyl)-N-methyl-
glycine, N-[(E)-aminoiminomethyl]-N-methyl-
Creatin
Creatine
CREATINE(P)
2-(1-methylguanidino)acetic acid
Kreatin
Krebiozon
cretine
MFCD00004282
((amino(imino)methyl)(methyl)amino)acetic acid
N-aminosarcosine
N-(AMINOIMINOMETHYL)-N-METHYL-GLYCINE
(a-Methylguanido)acetic Acid
EINECS 200-306-6
N-Carbamimidoyl-N-methylglycine

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
271.6±42.0 °C at 760 mmHg

[ Melting Point ]:
~295 °C (dec.)

[ Molecular Formula ]:
C4H9N3O2

[ Molecular Weight ]:
131.133

[ Flash Point ]:
118.1±27.9 °C

[ Exact Mass ]:
131.069473

[ PSA ]:
90.41000

[ LogP ]:
-1.88

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.552

[ Storage condition ]:
Store at RT.

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2925290090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Cyanamide
  • Sarcosine sodium salt
  • Calcium cyanamide
  • Creatinine
  • Sarcosine
  • Thiourea dioxide
  • L-Methionine
  • 2-Guanidinoacetic acid
  • Phosphocreatine
  • choline

DownStream

  • methylamine
  • (1-METHYL-4-OXO-4,5-DIHYDRO-1H-IMIDAZOL-2-YL)PHOSPHORAMIDIC DICHLORIDE
  • Glyoxylic acid
  • 1-Methylhydantoin
  • 2-Amino-3-Methyl-3H-Imidazo[4,5-F]Quinoline
  • Creatinine
  • Glycine,N-(aminoiminomethyl)-N-methyl-ethyl ester, hydrochloride (1:1)
  • ethyl acetate
  • N-methylguanidine
  • Oxalic acid

Customs

[ HS Code ]: 2925290090

[ Summary ]:
2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

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PLoS ONE 9(10) , e110115, (2014)

Hsp104 is a hexameric AAA+ protein that utilizes energy from ATP hydrolysis to dissolve disordered protein aggregates as well as amyloid fibers. Interestingly, Hsp104 orthologues are found in all king...

BRF1 mutations alter RNA polymerase III-dependent transcription and cause neurodevelopmental anomalies.

Genome Res. 25(2) , 155-66, (2015)

RNA polymerase III (Pol III) synthesizes tRNAs and other small noncoding RNAs to regulate protein synthesis. Dysregulation of Pol III transcription has been linked to cancer, and germline mutations in...

Propofol increases morbidity and mortality in a rat model of sepsis.

Crit. Care 19 , 45, (2015)

Severe sepsis is associated with approximately 50% mortality and accounts for tremendous healthcare costs. Most patients require ventilatory support and propofol is commonly used to sedate mechanicall...


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Related Compounds

  • Creatine-d3
  • Creatine HCL
  • CREATINE MALATE
  • Creatine Malate
  • CREATINEOROTATE
  • Phosphocreatine
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  • 1-Chloro-2-(3-fluorophenoxy)benzene
  • 2-(2,4-dioxo-8-oxa-1,3-diazaspiro[4.5]dec-3-yl)-N-(4-methylbenzyl)acetamide
  • 2-(2,4-dioxo-8-oxa-1,3-diazaspiro[4.5]dec-3-yl)-N-(4-methylcyclohexyl)acetamide
  • (2R)-2-methyl-3-(trifluoroacetamido)propanoic acid
  • 4,4,5,5-Tetramethyl-2-(4-methylpentyl)-1,3,2-dioxaborolane
  • (3R)-3-(2,6-difluorophenyl)-3-hydroxypropanoic acid
  • (2-Chloro-5-nitro-pyrimidin-4-yl)-(4-iodo-phenyl)-amine
  • Methyl 5-heptyldodecanoate
  • 5-Heptyldodecanoic acid