sucrose

Names

[ CAS No. ]:
57-50-1

[ Name ]:
sucrose

[Synonym ]:
GNE 410
Microse
amerfand
D(+)-Sucrose
SACCHARUM
sugar powder
SUGAR
Micr
Sugartab
SUCROSE
Surose
MFCD00006626
EINECS 200-334-9
Amerfond
α-D-Glc-(1→2)-β-D-Fru

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Boiling Point ]:
697.1±55.0 °C at 760 mmHg

[ Melting Point ]:
185-187 °C(lit.)

[ Molecular Formula ]:
C₁₂H₂₂O₁₁

[ Molecular Weight ]:
342.297

[ Flash Point ]:
375.4±31.5 °C

[ Exact Mass ]:
342.116211

[ PSA ]:
189.53000

[ LogP ]:
-3.48

[ Vapour Pressure ]:
0.0±5.0 mmHg at 25°C

[ Index of Refraction ]:
1.656

[ Water Solubility ]:
1970 g/L (15 ºC)

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WN6500000

CHEMICAL NAME :: Sucrose

CAS REGISTRY NUMBER :: 57-50-1

LAST UPDATED :: 199712

DATA ITEMS CITED :: 36

MOLECULAR FORMULA :: C12-H22-O11

MOLECULAR WEIGHT :: 342.34

WISWESSER LINE NOTATION :: T6OTJ CQ DQ EQ F1Q BO- BT5OTJ B1Q CQ DQ E1Q -GLU,FRUC

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 29700 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - cyanosis Gastrointestinal - hypermotility, diarrhea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 14000 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - domestic

DOSE/DURATION :: 40 gm/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - respiratory stimulation Gastrointestinal - hypermotility, diarrhea

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 1548 gm/kg

SEX/DURATION :: female 21 day(s) pre-mating female 1-22 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - Central Nervous System

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 683 gm/kg

SEX/DURATION :: female 1-21 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - hepatobiliary system Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 683 gm/kg

SEX/DURATION :: lactating female 21 day(s) post-birth

TOXIC EFFECTS :: Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 54810 mg/kg

SEX/DURATION :: female 15-35 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Rodent - hamster Ovary

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 189,15,1987 *** REVIEWS *** ACGIH TLV-Not classifiable as a human carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 10 mg/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD:NUISANCE PARTICULATES DTLWS* "Documentation of the Threshold Limit Values for Substances in Workroom Air," Supplements. For publisher information, see 85INA8. Volume(issue)/page/year: 3,28,1973 OSHA PEL (Gen Indu):8H TWA 15 mg/m3, total dust CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Gen Indu):8H TWA 5 mg/m3, respirable dust CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 15 mg/m3, total dust CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Construc):8H TWA 5 mg/m3, respirable dust CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 15 mg/m3, total dust CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Shipyard):8H TWA 5 mg/m3, respirable dust CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 15 mg/m3, total dust CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 OSHA PEL (Fed Cont):8H TWA 5 mg/m3, respirable dust CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 10 mg/m3 JAN 1993 OEL-BELGIUM:TWA 10 mg/m3 JAN 1993 OEL-FRANCE:TWA 10 mg/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 10 mg/m3 JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO SUCROSE, respirable fraction-air:10H TWA 5 mg/m3 REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO SUCROSE, total dust-air:10H TWA 10 mg/m3 REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81515 No. of Facilities: 12044 (estimated) No. of Industries: 101 No. of Occupations: 86 No. of Employees: 121005 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81515 No. of Facilities: 15179 (estimated) No. of Industries: 108 No. of Occupations: 110 No. of Employees: 368912 (estimated) No. of Female Employees: 169962 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
WN6500000

[ HS Code ]:
1701991090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

2,3,3',4,6-penta-O-benzylsucrose
mumeose E
Sucrose octaacetate
2,3,4,6-Tetra-O-benzyl-D-glucopyranose
ethyl 2-thio-β-D-fructofuranoside
ethyl 6-O-tert-butyldimethylsilyl-2-thio-β-D-fructofuranoside
ethyl 3-O-benzyl-6-O-tert-butyldimethylsilyl-2-thio-β-D-fructofuranoside
ethyl 3-O-benzyl-6-O-tert-butyldiphenylsilyl-2-thio-β-D-fructofuranoside

DownStream

5-(1-hydroxy-ethyl)-tetrahydro-furan-3-ol
hexane-1,2,5-triol
5-hydroxymethylfurfural
Levoglucosan
Sucralose
D-Galactose
STACHYOSE
Raffinose

Customs

[ HS Code ]: 1701991090

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C-Sucrose
Polysucrose
D-Sucrose-d6
Iron sucrose
Sucroselaurat
Sucrose monod
[(2,3,5,6-Tetrafluorophenyl)methyl]hydrazine
3-(1-Ethyl-5-oxopyrrolidin-2-yl)propanoic acid
[(2,3,5-Triiodophenyl)methyl]hydrazine
N-(4-Oxazol-5-yl-phenyl)-N'-pyridin-4-ylmethylene-hydrazine
Tert-butyl [1-[4-(methoxycarbonyl)phenyl]-3-tert-butyl-1H-pyrazol-5-yl]carbamate
ethyl 5-(methoxymethyl)-1H-1,2,4-triazole-3-carboxylate
1-(2,4,6-Trifluorophenyl)cyclopropane-1-carbonitrile
Ethyl 1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-methyl-1h-pyrazole-3-carboxylate
Tert-butyl {1-[4-(phenylethynyl)phenyl]cyclobutyl}carbamate
N-[3-(Phenylmethoxy)phenyl]benzenemethanamine

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