(R)-3-Chloro-1,2-propanediol

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Names

[ CAS No. ]:
57090-45-6

[ Name ]:
(R)-3-Chloro-1,2-propanediol

[Synonym ]:
(2R)-3-chloropropane-1,2-diol
(R)-α-Glycerol chlorohydrin
1,2-Propanediol, 3-chloro-, (2R)-
(2R)-(-)-3-Ch​loro-1,2-​propanedi​ol
(2R)-3-Chloro-1,2-propanediol
(2R)-(-)-3-Ch​loropropane-1,2-di​ol
1,2-Propa​nediol, 3​-chloro-,​ (2R)-(-)-
(R)-(-)-3-Chloro-1,2-propanediol
(R)-3-Chloro-1,2-propanediol
1,2-Propanediol, 3-chloro-, (R)-
Q1YQ1G &&(R)-(-)- Form
EINECS 435-560-9
MFCD00135169

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
213.0±0.0 °C at 760 mmHg

[ Melting Point ]:
-40ºC

[ Molecular Formula ]:
C3H7ClO2

[ Molecular Weight ]:
110.539

[ Flash Point ]:
113.3±21.8 °C

[ Exact Mass ]:
110.013458

[ PSA ]:
40.46000

[ LogP ]:
-0.76

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.474

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H318

[ Precautionary Statements ]:
P280-P301 + P310-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
T:Toxic

[ Risk Phrases ]:
R21;R23/25;R36/37/38;R62;R68

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 2689

[ WGK Germany ]:
3

[ RTECS ]:
TY4025000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2905590090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-chloro-3-hydroxypropan-2-one
  • Epichlorohydrin
  • (R)-(-)-Epichlorohydrin
  • (S)-(-)-PROPYLENEOXIDE
  • ALLYL CHLORIDE
  • (R)-(+)-4-Chloromethyl-2,2-Dimethyl-1,3-Dioxolane
  • 3-Chloro-1,2-propanediol
  • 1-CHLOROMETHYL-1,2-ETHANEDIOL DIACETATE
  • (S)-1,2-Diacetoxy-3-chloropropane

DownStream

  • (±)-Glycidol
  • (R)-(+)-4-Chloromethyl-2,2-Dimethyl-1,3-Dioxolane
  • (R)-2-(CHLOROMETHYL)-1,4-DIOXASPIRO[4.5]DECANE
  • (S)-3-HYDROXYETHYLMORPHOLINE

Customs

[ HS Code ]: 2905590090

[ Summary ]:
2905590090 other halogenated, sulphonated, nitrated or nitrosated derivatives of acyclic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Complete detoxification of tris(1,3-dichloro-2-propyl) phosphate by mixed two bacteria, Sphingobium sp. strain TCM1 and Arthrobacter sp. strain PY1.

J. Biosci. Bioeng. 113(1) , 79-83, (2012)

Tris(1,3-dichloro-2-propyl) phosphate (TDCPP), a flame retardant, is regarded as a potentially toxic and persistent environmental contaminant. We previously isolated a TDCPP-degrading bacterium, Sphin...

Passage of MHPG from plasma to CSF in a non-human primate.

Rev. Med. Chir. Soc. Med. Nat. Iasi. 115(4) , 1278-82, (2011)

In experimental protocols with humans and non-human primates, cerebrospinal fluid (CSF) concentrations of 3-methoxy-4-hydroxyphenylethylene glycol (MHPG), the predominant end-product of norepinephrine...

Fatty acid esters of monochloropropanediol (MCPD) and glycidol in refined edible oils.

Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 30(1) , 46-51, (2013)

Recently, fatty acid esters of monochloropropanediol (MCPD) and that of glycidol have been reported in refined edible oils. Since then a wealth of research has been published on the factors influencin...


More Articles

Related Compounds

  • (r)-3-chloro-1,2-propanediol
  • (R)-3-chloro-1-O-trityl-1,2-propanediol
  • (R)-2-butanoyl-1-phenylmethyl-3-chloro-1,2-propanediol
  • 3-Chloro-1,2-propanediol, di(trimethylsilyl) ether
  • 3-Chloro-1,2-propanediol
  • (R)-3-fluoro-1,2-propanediol acetonide
  • 4-Bromo-N-methyl-2-nitropyridin-3-amine
  • Ethyl 2-amino-3-(1-fluorocyclopropyl)-2-methylpropanoate
  • tert-butyl 4-[5-hydroxy-3-(propan-2-yl)-1H-1,2,4-triazol-1-yl]piperidine-1-carboxylate
  • tert-butyl N-[2-(2-hydroxyphenyl)ethyl]-N-[3-methyl-1-(pyridin-2-yl)butyl]carbamate
  • tert-butyl N-[(3-hydroxyphenyl)methyl]-N-(2-methylpropyl)carbamate
  • tert-butyl N-[1-(5-hydroxy-1H-1,2,4-triazol-3-yl)piperidin-4-yl]carbamate
  • tert-butyl N-[(3-hydroxyquinolin-4-yl)methyl]carbamate
  • tert-butyl N-[(8-hydroxyquinolin-5-yl)methyl]carbamate
  • tert-butyl N-[2-(2-hydroxypyrimidin-5-yl)ethyl]carbamate
  • tert-butyl N-[1-(5-bromo-2-hydroxypyridin-3-yl)cyclopropyl]carbamate
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