5α-Androstane-3β,17β-diol

Suppliers

Names

[ CAS No. ]:
571-20-0

[ Name ]:
5α-Androstane-3β,17β-diol

[Synonym ]:
Androstane-3,17-diol
3b,17b-Dihydroxy-5a-androstane
MFCD00064140
(3β,5α,17β)-Androstane-3,17-diol
3β-Androstanediol
3β androstanediol
5α-Androstane-3β,17β-diol
EINECS 209-334-3
5A-Androstan-3B,17B-diol
5α-Androstane-3β,17β-diol (8CI)
(3S,5S,8R,9S,10S,13S,14S,17S)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol
Androstane-3,17-diol, (3β,5α,17β)-
5alpha-androstane-3beta,17beta-diol
5a-Androstane-3b,17b-diol

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
415.0±18.0 °C at 760 mmHg

[ Melting Point ]:
121-128 °C(lit.)

[ Molecular Formula ]:
C19H32O2

[ Molecular Weight ]:
292.456

[ Flash Point ]:
186.0±15.8 °C

[ Exact Mass ]:
292.240234

[ PSA ]:
40.46000

[ LogP ]:
4.33

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.546

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BV8044320
CHEMICAL NAME :
5-alpha-Androstane-3-beta,17-beta-diol
CAS REGISTRY NUMBER :
571-20-0
BEILSTEIN REFERENCE NO. :
2559488
LAST UPDATED :
199709
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C19-H32-O2
MOLECULAR WEIGHT :
292.51

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
48 mg/kg
SEX/DURATION :
male 6 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands
REFERENCE :
JSTBBK Journal of Steroid Biochemistry. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 0BW, UK) V.1- 1969- Volume(issue)/page/year: 18,397,1983
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intramuscular
DOSE :
8 mg/kg
SEX/DURATION :
female 13-20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - urogenital system
REFERENCE :
ENDOAO Endocrinology (Baltimore). (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21203) V.1- 1917- Volume(issue)/page/year: 99,1490,1976

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/38

[ Safety Phrases ]:
S24-S45

[ RTECS ]:
BV8044320

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Androstenedione
  • Epiandrosterone
  • Epiandrosterone acetate
  • Allopregnanolone acetate
  • Stanolone
  • 5a-Androstanedione
  • 3β-acetoxy-17β-cyclohexanecarbonyloxy-5α-androstane
  • Androst-5-ene-3,17-diol,3-acetate 17-benzoate, (3b,17b)-
  • 3-acetyl-17-acetoxyandrost-2-ene

DownStream

  • Epiandrosterone
  • 5a-Androstanedione
  • Stanolone
  • androstane-3,7,17-triol
  • Androstenedione
  • (3S,5S,6S,8R,9S,1R,13S,14S,17S)-1,13-Dimethylhexadecahydro-1H-Cyclopenta[A]Phenanthrene-3,6,17-Triol
  • Etiocholanolone
  • Androsterone
  • Androstan-17-one,3-hydroxy-, (3b,5b)-
  • 5ALPHA-Androstane-3B,11B,17B-triol

Related Compounds

  • d3-5α-Androstane-3β,17β-diol
  • 17-Methyl-5α-androstane-3β,17β-diol
  • 4-Ethenylidene-5α-androstane-3β,17β-diol
  • 5,6α-epoxy-17α-methyl-5α-androstane-3β,17β-diol
  • 5β,6β-dihydro-1'H-azirino[5,6]-5α-androstane-3β,17β-diol
  • 5α,6α-dihydro-1'H-azirino[5,6]-5α-androstane-3β,17β-diol