(5R,8R,9S,10S,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
Names
[ CAS No. ]:
571-22-2
[ Name ]:
(5R,8R,9S,10S,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
[Synonym ]:
5beta,17beta-Hydroxyandrostan-3-one
5beta-Androstan-17beta-ol-3-one
Etiocholan-17beta-ol-3-one
5beta-Dihydrotestosterone
17beta-Hydroxyetiocholan-3-one
Chemical & Physical Properties
[ Density]:
1.085g/cm3
[ Boiling Point ]:
413.1ºC at 760 mmHg
[ Molecular Formula ]:
C19H30O2
[ Molecular Weight ]:
290.44000
[ Flash Point ]:
176.4ºC
[ Exact Mass ]:
290.22500
[ PSA ]:
37.30000
[ LogP ]:
3.95910
[ Index of Refraction ]:
1.536
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BV8054000
- CHEMICAL NAME :
- 5-beta-Androstan-3-one, 17-beta-hydroxy-
- CAS REGISTRY NUMBER :
- 571-22-2
- LAST UPDATED :
- 199206
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C19-H30-O2
- MOLECULAR WEIGHT :
- 290.49
- WISWESSER LINE NOTATION :
- L E5 B666 OVTJ A1 E1 FQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 240 mg/kg/5D-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 160 mg/kg
- SEX/DURATION :
- female 12-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - skin and skin appendages Reproductive - Effects on Newborn - delayed effects
MUTATION DATA
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 50 umol/L
- REFERENCE :
- PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 146,401,1974
Safety Information
[ Risk Phrases ]:
45-46-61-20/21/22
[ RTECS ]:
BV8054000