Maytansinol

Suppliers

Names

[ Name ]:
Maytansinol

[Synonym ]:
4,24-Dioxa-9,22-diazatetracyclo[19.3.1.1.0]hexacosa-10,12,14(26),16,18-pentaene-8,23-dione, 11-chloro-6,21-dihydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-, (1S,2R,3S,5S,6S,16E,18E,20R,21S) 
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Ansamitocin P0
O3-de-(N-acetyl-N-methyl-L-alanyl)-maytansine
(3E,5E,7R,84S)-14-chloro-10t,11c-epoxy-84,12c-dihydroxy-15,7r-dimethoxy-3,9c,11t,15-tetramethyl-(84r'H,86c'H)-15-aza-1(1,3)-benzena-8(4,6)-[1,3]oxazinana-cyclopentadecaphane-3,5-diene-82,14-dione
(1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-Chloro-6,21-dihydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1.0]hexacosa-10(26),11,13,16,18-pentaene-8,23-dione
Maytansinol (7)

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
835.8±65.0 °C at 760 mmHg

[ Melting Point ]:
>153C (dec.)

[ Molecular Formula ]:
C₂₈H₃₇ClN₂O₈

[ Molecular Weight ]:
565.055

[ Flash Point ]:
459.3±34.3 °C

[ Exact Mass ]:
564.223816

[ PSA ]:
130.09000

[ LogP ]:
3.73

[ Vapour Pressure ]:
0.0±3.2 mmHg at 25°C

[ Index of Refraction ]:
1.607

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

maytanbutine
(2Z,4E)-2-formyl-5-methoxypenta-2,4-dienenitrile
(14S,16S,2R,3E,5E,12S,13E,15S)-84-chloro-12-hydroxy-14,85,2-trimethoxy-6,9,13,15-tetramethyl-9-aza-1(4,6)-oxazinana-8(1,3)-benzenacyclopentadecaphane-3,5,13-triene-12,10-dione
(5S,6E,8S,9S,12R,13E,15E)-5-((tert-butyldimethylsilyl)oxy)-6-chloro-9-hydroxy-5,12-dimethoxy-2,6,8,16-tetramethylspiro[2-aza-1(1,3)-benzenacycloheptadecaphanene-11,2'-[1,3]dithiane]-6,13,15-trien-3-one
(5S,6E,8S,9S,12R,13E,15E)-5-((tert-butyldimethylsilyl)oxy)-6-chloro-5,12-dimethoxy-2,6,8,16-tetramethyl-3-oxospiro[2-aza-1(1,3)-benzenacycloheptadecaphanene-11,2'-[1,3]dithiane]-6,13,15-trien-9-yl carbamate
Ansamitocin P-3
(-)-maytansinol