Maytansinol

Suppliers

Names

[ CAS No. ]:
57103-68-1

[ Name ]:
Maytansinol

[Synonym ]:
4,24-Dioxa-9,22-diazatetracyclo[19.3.1.1.0]hexacosa-10,12,14(26),16,18-pentaene-8,23-dione, 11-chloro-6,21-dihydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-, (1S,2R,3S,5S,6S,16E,18E,20R,21S) 
-
Ansamitocin P0
O3-de-(N-acetyl-N-methyl-L-alanyl)-maytansine
(3E,5E,7R,84S)-14-chloro-10t,11c-epoxy-84,12c-dihydroxy-15,7r-dimethoxy-3,9c,11t,15-tetramethyl-(84r'H,86c'H)-15-aza-1(1,3)-benzena-8(4,6)-[1,3]oxazinana-cyclopentadecaphane-3,5-diene-82,14-dione
(1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-Chloro-6,21-dihydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1.0]hexacosa-10(26),11,13,16,18-pentaene-8,23-dione
Maytansinol (7)

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
835.8±65.0 °C at 760 mmHg

[ Melting Point ]:
>153C (dec.)

[ Molecular Formula ]:
C28H37ClN2O8

[ Molecular Weight ]:
565.055

[ Flash Point ]:
459.3±34.3 °C

[ Exact Mass ]:
564.223816

[ PSA ]:
130.09000

[ LogP ]:
3.73

[ Vapour Pressure ]:
0.0±3.2 mmHg at 25°C

[ Index of Refraction ]:
1.607

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • maytanbutine
  • (2Z,4E)-2-formyl-5-methoxypenta-2,4-dienenitrile
  • (14S,16S,2R,3E,5E,12S,13E,15S)-84-chloro-12-hydroxy-14,85,2-trimethoxy-6,9,13,15-tetramethyl-9-aza-1(4,6)-oxazinana-8(1,3)-benzenacyclopentadecaphane-3,5,13-triene-12,10-dione
  • (5S,6E,8S,9S,12R,13E,15E)-5-((tert-butyldimethylsilyl)oxy)-6-chloro-9-hydroxy-5,12-dimethoxy-2,6,8,16-tetramethylspiro[2-aza-1(1,3)-benzenacycloheptadecaphanene-11,2'-[1,3]dithiane]-6,13,15-trien-3-one
  • (5S,6E,8S,9S,12R,13E,15E)-5-((tert-butyldimethylsilyl)oxy)-6-chloro-5,12-dimethoxy-2,6,8,16-tetramethyl-3-oxospiro[2-aza-1(1,3)-benzenacycloheptadecaphanene-11,2'-[1,3]dithiane]-6,13,15-trien-9-yl carbamate
  • Ansamitocin P-3
  • (-)-maytansinol

DownStream

  • Ansamitocin P-3
  • Mertansine
  • Ansamitocin P-3

Related Compounds

  • (-)-maytansinol
  • Maytansinol butyrate
  • Maytansinol butyrate
  • O3-acetyl-maytansinol
  • Maytansinol propionate
  • N-Me-L-Ala-maytansinol
  • (E)-N-(2-(3-fluorophenyl)-2-methoxyethyl)-3-(thiophen-2-yl)acrylamide
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 2-(Methyl(piperidin-3-ylmethyl)amino)-1-(thiophen-2-yl)ethanone hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(2-(1-(thieno[3,2-d]pyrimidin-4-yl)piperidin-4-yl)ethyl)pivalamide
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde