Acetic acid,trimethylplumbyl ester

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Names

[ Name ]:
Acetic acid,trimethylplumbyl ester

[Synonym ]:
Acetoxytrimethylplumbane
Trimethylbleiacetat
Plumbane,acetoxytrimethyl
EINECS 227-200-2
Lead,acetoxytrimethyl
MFCD00014973
trimethyllead acetate

Chemical & Physical Properties

[ Melting Point ]:
180ºC (dec.)(lit.)

[ Molecular Formula ]:
C₅H₁₂O₂Pb

[ Molecular Weight ]:
311.34800

[ Exact Mass ]:
312.06000

[ PSA ]:
26.30000

[ LogP ]:
1.38440

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TP3922100

CHEMICAL NAME :: Plumbane, acetoxytrimethyl-

CAS REGISTRY NUMBER :: 5711-19-3

LAST UPDATED :: 199712

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C5-H12-O2-Pb

MOLECULAR WEIGHT :: 311.36

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 66 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold

REFERENCE :: APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 24,17,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 82 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold

REFERENCE :: APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 24,17,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 34 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold

REFERENCE :: APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 24,17,1966

Safety Information

[ Hazard Codes ]:
T+,N

[ Risk Phrases ]:
61-26/27/28-33-50/53-62

[ Safety Phrases ]:
S45;S53;S60;S61

[ RIDADR ]:
UN 2811 6.1/PG 2

Related Compounds

2-Propenoic acid,trimethylplumbyl ester
(E)-3-methyl-6-(toluene-4-sulfonyloxy)hex-2-enol acetic acid ester
Phosphonic acid, (2,2,2-trichloro-1-hydroxyethyl)-, diethyl ester, ace tate
chloracetophos
acetic acid ethyl ester, deprotonated form
Acetic acid,diethyloctylstannyl ester
2-ethoxy-N-((3-(5-methylisoxazol-3-yl)-1,2,4-oxadiazol-5-yl)methyl)acetamide
5-bromo-2-chloro-N-((3-(5-methylisoxazol-3-yl)-1,2,4-oxadiazol-5-yl)methyl)benzamide
N-((3-(5-methylisoxazol-3-yl)-1,2,4-oxadiazol-5-yl)methyl)furan-2-carboxamide
2-(2,4-difluorophenyl)-N-((3-(5-methylisoxazol-3-yl)-1,2,4-oxadiazol-5-yl)methyl)acetamide
N-((3-(5-methylisoxazol-3-yl)-1,2,4-oxadiazol-5-yl)methyl)benzo[b]thiophene-2-carboxamide
N-((3-(5-methylisoxazol-3-yl)-1,2,4-oxadiazol-5-yl)methyl)-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxamide
3-(3,5-dimethylisoxazol-4-yl)-N-((3-(6-ethoxypyridin-3-yl)-1,2,4-oxadiazol-5-yl)methyl)propanamide
N-((3-(6-ethoxypyridin-3-yl)-1,2,4-oxadiazol-5-yl)methyl)-2-(ethylthio)benzamide
N-((3-(6-ethoxypyridin-3-yl)-1,2,4-oxadiazol-5-yl)methyl)-2-((4-fluorophenyl)thio)acetamide
N-((2-methyl-2,4,5,6-tetrahydrocyclopenta[c]pyrazol-3-yl)methyl)-2-oxoimidazolidine-1-carboxamide

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