Norfluoxetine hydrochloride

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Names

[ CAS No. ]:
57226-68-3

[ Name ]:
Norfluoxetine hydrochloride

[Synonym ]:
3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine,hydrochloride
Benzenepropanamine, γ-(4-(trifluoromethyl)phenoxy)-, hydrochloride
3-Phenyl-3-[4-(trifluoromethyl)phenoxy]-1-propanamine hydrochloride (1:1)
Benzenepropanamine, γ-[4-(trifluoromethyl)phenoxy]-, hydrochloride (1:1)

Chemical & Physical Properties

[ Density]:
1.204g/cm3

[ Boiling Point ]:
381.1ºC at 760 mmHg

[ Molecular Formula ]:
C16H17ClF3NO

[ Molecular Weight ]:
331.760

[ Flash Point ]:
184.3ºC

[ Exact Mass ]:
331.095062

[ PSA ]:
35.25000

[ LogP ]:
5.67660

[ Water Solubility ]:
H2O: >4 mg/mL

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac.

Science 347(6227) , 1256-9, (2015)

TREK-2 (KCNK10/K2P10), a two-pore domain potassium (K2P) channel, is gated by multiple stimuli such as stretch, fatty acids, and pH and by several drugs. However, the mechanisms that control channel g...

The pH-dependent toxicity of basic pharmaceuticals in the green algae Scenedesmus vacuolatus can be explained with a toxicokinetic ion-trapping model.

Aquat. Toxicol. 101(1) , 266-75, (2011)

Several previous studies revealed that pharmaceuticals with aliphatic amine function exhibit a higher toxicity toward algae than toward other aquatic organisms. Here we investigated the pH-dependent t...

Sequential metabolism of secondary alkyl amines to metabolic-intermediate complexes: opposing roles for the secondary hydroxylamine and primary amine metabolites of desipramine, (s)-fluoxetine, and N-desmethyldiltiazem.

Drug Metab. Dispos. 38(6) , 963-72, (2010)

Three secondary amines desipramine (DES), (S)-fluoxetine [(S)-FLX], and N-desmethyldiltiazem (MA) undergo N-hydroxylation to the corresponding secondary hydroxylamines [N-hydroxydesipramine, (S)-N-hyd...


More Articles

Related Compounds

  • norfluoxetine hydrochloride
  • Norfluoxetine-d5 hydrochloride
  • norfluoxetine oxalate
  • Norfluoxetine-d5
  • carnitine hydrochloride
  • Losoxantrone hydrochloride [USAN]
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
  • N-[3-(Aminooxy)propyl]-N-butyl-1-butanamine