3-methylcyclobutane-1-carboxylic acid

Suppliers

Names

[ CAS No. ]:
57252-83-2

[ Name ]:
3-methylcyclobutane-1-carboxylic acid

[Synonym ]:
3-n-methylcyclobutane-1-carboxylic acid
Diethyl-3-methylcyclobutan-1,1-dicarboxylat
3-Methyl-cyclobutancarbonsaeure
3-Methyl-cyclobutan-1,1-dicarbonsaeure-diaethylester
3-methylcyclobutylcarboxylic acid
3-methyl-cyclobutane-1,1-dicarboxylic acid diethyl ester
3-Methyl-cyclobutan-1-carbonsaeure
3-methyl-cyclobutanecarboxylic acid
3-Methyl-1,1-cyclobutandicarbonsaeure-diaethylester
3-methylcyclobutane-1-carboxylic acid

Chemical & Physical Properties

[ Density]:
1.105g/cm3

[ Boiling Point ]:
194ºC at 760mmHg

[ Molecular Formula ]:
C6H10O2

[ Molecular Weight ]:
114.14200

[ Flash Point ]:
87.7ºC

[ Exact Mass ]:
114.06800

[ PSA ]:
37.30000

[ LogP ]:
1.11710

[ Index of Refraction ]:
1.478

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GU1349000
CHEMICAL NAME :
Cyclobutanecarboxylic acid, 3-methyl-
CAS REGISTRY NUMBER :
57252-83-2
LAST UPDATED :
199106
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C6-H10-O2
MOLECULAR WEIGHT :
114.16

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 12,501,1977

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2916209090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-methoxycarbonyl-3-methyl-2-(N-piperidinyl)cyclobutane
  • 3-Methylenecyclobutanecarbonitrile
  • diethyl 3-methylcyclobutane-1,1-dicarboxylate
  • 3-Methyl-1,1-cyclobutandicarbonsaeure
  • 3-methyl-cyclobutanecarbonitrile
  • 1,3-Dibromo-2-methylpropane
  • Diethyl malonate
  • 1-Bromo-3-chloro-2-methylpropane
  • sodium 1,3-diethoxy-1,3-dioxopropan-2-ide

DownStream

  • tert-butyl N-(3-methylcyclobutyl)carbamate
  • 3-Methylcyclobutanone
  • Cyclobutanecarboxamide, N,N,3-trimethyl- (7CI,9CI)
  • ethyl 3-methylcyclobutane-1-carboxylate
  • trans-3-methyl-1-chlorocyclobutane
  • 1-chloro-3-methylcyclobutane

Customs

[ HS Code ]: 2916209090

[ Summary ]:
2916209090 other cyclanic, cyclenic or cyclotherpenic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Related Compounds

  • 3-ethyl-3-methylcyclobutane-1-carboxylic acid
  • 1-Amino-3-methylcyclobutane-1-carboxylic acid
  • 3-hydroxy-3-methylcyclobutane-1-carboxylic acid
  • trans-3-fluoro-3-methylcyclobutane-1-carboxylic acid
  • (1s,3s)-1-Amino-3-methylcyclobutane-1-carboxylic acid
  • 3,3-difluoro-1-methylcyclobutane-1-carboxylic acid