1-(3,4-Dichlorophenyl)piperazine

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Names

[ CAS No. ]:
57260-67-0

[ Name ]:
1-(3,4-Dichlorophenyl)piperazine

[Synonym ]:
1-(3,4-dichloro-phenyl)-piperazine
Piperazine,1-(3,4-dichlorophenyl)
MFCD00023128
1,2-Dichloro-4-(1-piperazino)benzene
1-(3,4-difchlorophenyl)piperazine
4-(3,4-dichlorophenyl)piperazine
3,4-dichlorophenylpiperazine
N-(3,4-Dichlorophenyl)piperazine
EINECS 260-652-9
1-(3,4-dichloropheny)piperazine
RARECHEM AH CK 0083
Piperazine, 1-(3,4-dichlorophenyl)-
1-(3,4-Dichlorophenyl)piperazine

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
370.1±42.0 °C at 760 mmHg

[ Melting Point ]:
62-66 °C

[ Molecular Formula ]:
C10H12Cl2N2

[ Molecular Weight ]:
231.122

[ Flash Point ]:
177.6±27.9 °C

[ Exact Mass ]:
230.037750

[ PSA ]:
15.27000

[ LogP ]:
2.67

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.570

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S24/25

[ RIDADR ]:
3259

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
29335995

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Bis(2-Chloroethyl)amine hydrochloride
  • 3,4-Dichloroaniline
  • Piperazine
  • 4-Bromo-1,2-dichlorobenzene
  • 1-Boc-4-(3,4-dichlorophenyl)piperazine

DownStream

  • 5-[[4-(3,4-dichlorophenyl)piperazin-1-yl]methyl]-4,5-dihydro-1,3-oxazol-2-amine
  • 4-[4-(3,4-dichlorophenyl)piperazin-1-yl]pyridin-3-amine
  • 2-[2-[4-(3,4-dichlorophenyl)piperazin-1-yl]ethyl]quinoline

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Synthesis and Anti-inflammatory Performance of Newly Cyclizine Derivatives on Adult Male Wistar Rats.

Iran. J. Pharm. Res. 11 , 1027-37, (2013)

Cyclizine (1-benzhydryl-4-methyl-piperazine, CAS 82-92-8, CYC, I), a piperazine derivative, belongs to H1 antihistamine group of drugs that shows such pharmacological properties as anti-inflammatory, ...

Yaws CL.

The Yaws Handbook of Physical Properties for Hydrocarbons and Chemicals 2nd ed.,, (2015), 282


More Articles

Related Compounds

  • 1-(3,4-DICHLOROPHENYL)PIPERAZINEHYDROCHLORIDE
  • 1-(3,4-Dichlorophenyl)piperazine hydrochloride
  • 1-(3,4-dichlorophenyl)-4-(3-methoxypropyl)piperazine,sulfuric acid
  • 1-(3,4-Dichlorophenyl)-4-(5-nitro-2-pyridinyl)piperazine
  • 1-(3,4-Dichlorophenyl)-4-(2,4,4-trimethylallophanoyl)piperazine
  • 1-(3,4-dichlorophenyl)-4-(3-nitropyridin-4-yl)piperazine
  • L-Tyrosylglycyl-L-alanyl-L-phenylalanyl-L-methionine
  • 7-[(5-methylfuran-2-yl)methyl]-6-({[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl}sulfanyl)-2H,7H,8H-[1,3]dioxolo[4,5-g]quinazolin-8-one
  • N-[6-(isopropylsulfonyl)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl]-2-methoxybenzamide
  • 4-bromo-2-fluoro-N-(2-hydroxypropyl)benzamide
  • 3-(4-chlorophenyl)-9-isobutyl-5,7-dimethyl-5H-[1,2,4]triazolo[4,3-e]purine-6,8(7H,9H)-dione
  • N-[4-({[5-(1,3-benzodioxol-5-yl)-1,3,4-oxadiazol-2-yl]methyl}thio)phenyl]-2,2-dimethylpropanamide
  • 2-methyl-N-(1-methyl-2-oxoindolin-5-yl)propane-1-sulfonamide
  • 1,5-dioxo-N-[(2Z)-5-propyl-1,3,4-thiadiazol-2(3H)-ylidene]-2,3,4,5-tetrahydropyrrolo[1,2-a]quinazoline-3a(1H)-carboxamide
  • 2-(3-(3,5-dimethyl-1H-pyrazol-1-yl)-6-oxopyridazin-1(6H)-yl)-N-(3,3-diphenylpropyl)acetamide
  • 3-(1H-indol-1-yl)-N-[(2Z)-5-(methoxymethyl)-1,3,4-thiadiazol-2(3H)-ylidene]propanamide
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