n4-aminocytidine

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Names

[ CAS No. ]:
57294-74-3

[ Name ]:
n4-aminocytidine

[Synonym ]:
N-Aminocytidine
N4-aminocytidine minimum
N4-NH2-Cr
n(sup4)-aminocytidine
uridine,4-hydrazone

Chemical & Physical Properties

[ Density]:
1.93g/cm3

[ Boiling Point ]:
555.5ºC at 760mmHg

[ Melting Point ]:
>160 °C(sublime)

[ Molecular Formula ]:
C₉H₁₆N₄O₅

[ Molecular Weight ]:
260.24700

[ Flash Point ]:
289.8ºC

[ Exact Mass ]:
260.11200

[ PSA ]:
140.31000

[ Index of Refraction ]:
1.776

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YU8055000

CHEMICAL NAME :: Uridine, 4-hydrazone

CAS REGISTRY NUMBER :: 57294-74-3

LAST UPDATED :: 199410

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C9-H14-N4-O5

MOLECULAR WEIGHT :: 258.27

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Specific locus test

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 50 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 177,283,1987

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H332

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
T

[ Risk Phrases ]:
46-20/21/22

[ Safety Phrases ]:
53-22-36/37/39-45

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
YU8055000

[ HS Code ]:
29335990

Articles

Genotoxic properties of representatives of alkylindazoles and aminoalkyl-indoles which are consumed as synthetic cannabinoids.

Food Chem. Toxicol. 80 , 130-6, (2015)

Synthetic cannabinoids (SCs) cause similar effects as cannabis and are sold in herbal mixtures. Recent investigations indicate that some of these drugs possess genotoxic properties. Therefore, we test...

Mutagenic nucleoside analog N4-aminocytidine: metabolism, incorporation into DNA, and mutagenesis in Escherichia coli.

J. Bacteriol. 170(11) , 5257-62, (1988)

N4-Aminocytidine, a nucleoside analog, is strongly mutagenic to various organisms including Escherichia coli. Using E. coli WP2 (trp), we measured the incorporation of [5-3H]N4-aminocytidine into DNA ...

An improved synthesis of N4-aminocytidine.

Chem. Pharm. Bull. 35(9) , 3884-7, (1987)

N4-aminocytidine minimum
N4-methyl-N4-aminocytidine
N4-methyl-N4-aminocytidine
N4-Benzoyl-1-(4',6'-di-O-acetyl-2',3'-dideoxy-β-D-glucopyranosyl)cytosin
N4-benzyl-N1,N7-ditosyl-4-aza-1,7-heptanediamine
N4-(4-nitrophenyl)pyrimidine-4,5,6-triamine