PYROQUILON

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Names

[ CAS No. ]:
57369-32-1

[ Name ]:
PYROQUILON

[Synonym ]:
1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one
Pyroquilone [ISO-French]
Coratop
1,2,5,6-tetrahydropyrrolo[3,2,1-ij]quinolin-4-one
Pyroquilon [BSI:ISO]
1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]-quinolin-4-one
Lilolidone
Fongorene
MFCD00078738
4-oxo-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinoline
Pyroquilone
Fongoren
Pyroquilon
1,2,5,6-tetrahydropyrrolo(3,2,1-ij)quinolin-4-one

Chemical & Physical Properties

[ Density]:
1.25g/cm3

[ Boiling Point ]:
355.2ºC at 760 mmHg

[ Melting Point ]:
112℃

[ Molecular Formula ]:
C11H11NO

[ Molecular Weight ]:
173.21100

[ Flash Point ]:
173.7ºC

[ Exact Mass ]:
173.08400

[ PSA ]:
22.00000

[ LogP ]:
1.79050

[ Index of Refraction ]:
1.644

[ Storage condition ]:
0-6°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UY9480000
CHEMICAL NAME :
4H-Pyrrolo(3,2,1-ij)quinolin-4-one, 1,2,5,6-tetrahydro-
CAS REGISTRY NUMBER :
57369-32-1
BEILSTEIN REFERENCE NO. :
1455831
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C11-H11-N-O
MOLECULAR WEIGHT :
173.23

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
321 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,746,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>3100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,746,1991

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H412

[ Precautionary Statements ]:
P273

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
61

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
UY9480000

[ HS Code ]:
2933499012

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Indoline
  • 3-Chloropropanoyl chloride
  • 3-CHLORO-1-(2,3-DIHYDRO-1H-INDOL-1-YL)PROPAN-1-ONE
  • methyl 3-(2,3-dihydroindol-7-yl)acrylate
  • 1-(7-iodo-2,3-dihydroindol-1-yl)ethanone
  • 2,3-dihydro-7-iodoindole
  • 1-BOC-INDOLINE

DownStream

  • 1,2,5,6-Tetrahydro-4H-pyrrolo(3,2,1-ij)quinoline
  • 8-bromo-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one
  • 8-acetyl-1,2,5,6-tetrahydro-pyrrolo[3,2,1-ij]quinolin-4-one

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%