Resiniferatoxin

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Names

[ CAS No. ]:
57444-62-9

[ Name ]:
Resiniferatoxin

[Synonym ]:
MFCD00135927
Resiniferatoxin,4-Hydroxy-3-methoxy-[(2S,3aR,3bS,6aR,9aR,9bR,10R,11aR)-3a,3b,6,6a,9a,10,11,11a-octahydro-6a-hydroxy-8,10-dimethyl-11a-(1-methylethenyl)-7-oxo-2-(phenylmethyl)-7H-2,9b-epoxyazuleno[5,4-e]-1,3-benzodioxol-5-yl]benzeneacetate

Chemical & Physical Properties

[ Density]:
1.35g/cm3

[ Boiling Point ]:
768.7ºC at 760mmHg

[ Molecular Formula ]:
C37H40O9

[ Molecular Weight ]:
628.71

[ Flash Point ]:
240.3ºC

[ Exact Mass ]:
628.26700

[ PSA ]:
120.75000

[ LogP ]:
4.74470

[ Index of Refraction ]:
1.643

[ Storage condition ]:
20°C

MSDS

Safety Information

[ Symbol ]:

GHS05, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
T

[ Risk Phrases ]:
25-35

[ Safety Phrases ]:
S26;S45;S36/S37/S39

[ RIDADR ]:
UN 2928 6.1/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
CY1633700

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1(a)

Articles

Activation of the TRPV1 cation channel contributes to stress-induced astrocyte migration.

Glia 62(9) , 1435-51, (2014)

Astrocytes provide metabolic, structural, and synaptic support to neurons in normal physiology and also contribute widely to pathogenic processes in response to stress or injury. Reactive astrocytes c...

TRPM5-dependent amiloride- and benzamil-insensitive NaCl chorda tympani taste nerve response.

Am. J. Physiol. Gastrointest. Liver Physiol. 305(1) , G106-17, (2013)

Transient receptor potential (TRP) subfamily M member 5 (TRPM5) cation channel is involved in sensing sweet, bitter, umami, and fat taste stimuli, complex-tasting divalent salts, and temperature-induc...

Inhibition by capsaicin and its related vanilloids of compound action potentials in frog sciatic nerves.

Life Sci. 92(6-7) , 368-78, (2013)

Although capsaicin not only activates transient receptor potential vanilloid-1 (TRPV1) channels but also inhibits nerve conduction, the latter action has not yet been fully examined. The purpose of th...


More Articles


Related Compounds

  • RESINIFERATOXIN
  • rac-1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl (3'R,4S)-2,3-dihydrospiro[1-benzopyran-4,1'-cyclopropane]-3'-carboxylate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 6-Ethynyl-5-fluoro-2-methyl-1,3-benzoxazole
  • rac-4-[(1R,2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentanecarbonyl]morpholine-3-carboxylic acid
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde