diethyl 2-(pyridin-3-ylmethyl)propanedioate

Names

[ CAS No. ]:
57477-12-0

[ Name ]:
diethyl 2-(pyridin-3-ylmethyl)propanedioate

[Synonym ]:
pyridin-3-ylmethyl-malonic acid diethyl ester
diethyl 3-picolylmalonate
EINECS 260-758-5

Chemical & Physical Properties

[ Density]:
1.132g/cm3

[ Boiling Point ]:
346.8ºC at 760mmHg

[ Molecular Formula ]:
C13H17NO4

[ Molecular Weight ]:
251.27800

[ Flash Point ]:
163.5ºC

[ Exact Mass ]:
251.11600

[ PSA ]:
65.49000

[ LogP ]:
1.36650

[ Index of Refraction ]:
1.499

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-(Chloromethyl)pyridine
  • Diethyl malonate
  • Nicotinaldehyde
  • sodium 1,3-diethoxy-1,3-dioxopropan-2-ide
  • 3-Chloromethylpyridinehydrochloride

DownStream

Related Compounds

  • diethyl 2-acetamido-2-(pyridin-3-ylmethyl)propanedioate
  • Ethyl α-Acetamido-α-carbethoxy-β-(7-aza-3-indolyl)propionate
  • diethyl 2-(thiophen-3-ylmethyl)propanedioate
  • diethyl 2-(pyridin-3-ylmethylene)malonate
  • diethyl 2-(1H-indol-3-ylmethyl)propanedioate
  • diethyl 2-amino-2-(1H-indol-3-ylmethyl)propanedioate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
  • 1-(2-(Dimethylamino)ethyl)-2,3-dimethyl-1,5,6,7,8,9-hexahydrocyclohepta[b]pyrrolo[3,2-e]pyridin-4-amine