(2S)-2-[(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)amino]-4-methylpentanoic acid,dihydrochloride
Names
[ CAS No. ]:
57533-05-8
[ Name ]:
(2S)-2-[(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)amino]-4-methylpentanoic acid,dihydrochloride
[Synonym ]:
L-Leucine-4-antipyrineamide dihydrochloride
WK 30 dihydrochloride
L-Leucine,N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-,dihydrochloride
(2S)-2-[(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)amino]-4-methylpentanoic acid dihydrochloride
Chemical & Physical Properties
[ Boiling Point ]:
469.6ºC at 760 mmHg
[ Molecular Formula ]:
C17H25Cl2N3O3
[ Molecular Weight ]:
390.30500
[ Flash Point ]:
237.8ºC
[ Exact Mass ]:
389.12700
[ PSA ]:
76.26000
[ LogP ]:
4.07260
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- OH3165500
- CHEMICAL NAME :
- L-Leucine, N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol -4-yl)-, dihydrochloride
- CAS REGISTRY NUMBER :
- 57533-05-8
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C17-H23-N3-O3.2Cl-H
- MOLECULAR WEIGHT :
- 390.35
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3010 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PMHBAH Polish Medical Sciences and History Bulletin. (Chicago, IL) V.1-15, 1956-76. Discontinued. Volume(issue)/page/year: 17(4),323,1974 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5600 mg/kg/56D-I
- TOXIC EFFECTS :
- Autonomic Nervous System - smooth muscle relaxant (mechanism undefined, spasmolytic) Behavioral - antipsychotic Blood - changes in leukocyte (WBC) count
- REFERENCE :
- PMHBAH Polish Medical Sciences and History Bulletin. (Chicago, IL) V.1-15, 1956-76. Discontinued. Volume(issue)/page/year: 17(4),323,1974