Cibenzoline succinate

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Names

[ CAS No. ]:
57625-97-5

[ Name ]:
Cibenzoline succinate

[Synonym ]:
2-(2,2-Diphenylcyclopropyl)-4,5-dihydro-1H-imidazole succinate (2:1)
Succinic acid,compound with 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1H-imidazole (1:2)
EINECS 260-856-8
Butanedioic acid,compd. with 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1H-imidazole (1:2)
1H-Imidazole,4,5-dihydro-2-(2,2-diphenylcyclopropyl)-,succinate (2:1)

Chemical & Physical Properties

[ Boiling Point ]:
449.2ºC at 760 mmHg

[ Molecular Formula ]:
C40H42N4O4

[ Molecular Weight ]:
642.78600

[ Flash Point ]:
225.5ºC

[ Exact Mass ]:
642.32100

[ PSA ]:
123.38000

[ LogP ]:
5.45320

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NI4804900
CAS REGISTRY NUMBER :
57625-97-5
LAST UPDATED :
199712
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C36-H36-N4.C4-H6-O4
MOLECULAR WEIGHT :
642.86

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - woman
DOSE/DURATION :
300 mg/kg/22W-I
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - ptosis Behavioral - muscle weakness
REFERENCE :
IEDIEP Internal Medicine. (The Japanese Society of Internal Medicine, 34-3, 3-chome, Hongo, Bunkyo-ku, Tokyo 113, Japan) V.31- 1992- Volume(issue)/page/year: 35,512,1996
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
41500 ug/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - ptosis Behavioral - altered sleep time (including change in righting reflex) Behavioral - convulsions or effect on seizure threshold
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 22,4485,1988

Related Compounds

  • cibenzoline succinate
  • Cibenzoline succinate
  • Cibenzoline
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