Fenobam

Suppliers

Names

[ Name ]:
Fenobam

[Synonym ]:
Mcn-3377
N-(3-Chlorophenyl)-N'-(4,5-dihydro-1-methyl-4-oxo-1H-imidazole-2-yl)urea
1-(3-chlorophenyl)-3-(1-methyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl)urea
N-(3-chlorophenyl)-N'-(4,5-dihydro-1-methyl-4-oxo-1H-imidazole-2-yl)urea
1-(3-Chlorophenyl)-3-(4,5-dihydro-1-methyl-4-oxo-1H-imidazol-2-yl)urea
[3H]-Fenobam
N-3-chlorophenyl-N'-(4,5-dihydro-1-methyl-4-oxo-1H-imidazol-2-yl)urea

Chemical & Physical Properties

[ Density]:
1.47 g/cm3

[ Molecular Formula ]:
C₁₁H₁₁ClN₄O₂

[ Molecular Weight ]:
266.68400

[ Exact Mass ]:
266.05700

[ PSA ]:
73.80000

[ LogP ]:
1.12690

[ Index of Refraction ]:
1.668

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H300

[ Precautionary Statements ]:
Missing Phrase - N15.00950417

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ RIDADR ]:
UN 2811 6.1 / PGIII

Articles

Pharmacophoric features of drugs with guanylurea moiety: an electronic structure analysis.

J. Mol. Model. 19(4) , 1865-74, (2013)

Several therapeutically important compounds contain guanylurea (GU) moiety. The appropriate tautomeric state of these species has not been explored, preliminary studies indicated that the traditional ...

Inhibition of Group I Metabotropic Glutamate Receptors Reverses Autistic-Like Phenotypes Caused by Deficiency of the Translation Repressor eIF4E Binding Protein 2.

J. Neurosci. 35 , 11125-32, (2015)

Exacerbated mRNA translation during brain development has been linked to autism spectrum disorders (ASDs). Deletion of the eukaryotic initiation factor 4E (eIF4E)-binding protein 2 gene (Eif4ebp2), en...

Insights into the interaction of negative allosteric modulators with the metabotropic glutamate receptor 5: discovery and computational modeling of a new series of ligands with nanomolar affinity.

Bioorg. Med. Chem. 23 , 3040-58, (2015)

Metabotropic glutamate receptor 5 (mGlu5) is a biological target implicated in major neurological and psychiatric disorders. In the present study, we have investigated structural determinants of the i...

Fenobam (USAN)
2-Trifluoromethoxy-4-formylphenyl boronic acid
2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)(methyl)amino)propan-1-ol
(1-methyl-1H-1,2,3-triazol-4-yl)(4-(thiophen-2-yl)piperidin-1-yl)methanone
(2-((Difluoromethyl)sulfonyl)phenyl)(4-(thiophen-3-yl)piperidin-1-yl)methanone
(1-methyl-1H-1,2,3-triazol-4-yl)(4-(thiophen-3-yl)piperidin-1-yl)methanone
(3-Fluoro-4-methoxyphenyl)(4-(thiophen-3-yl)piperidin-1-yl)methanone
1-(4-(Thiophen-3-yl)piperidine-1-carbonyl)imidazolidin-2-one
3-Ethynyl-6-fluoro-2-methylpyridine
3-(2-Fluorophenyl)-1-(4-(thiophen-3-yl)piperidin-1-yl)propan-1-one
D-Leucine, N-[[ethyl(3-methylphenyl)amino]carbonyl]-

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