Methyl 2-sulfamoylbenzoate

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Names

[ CAS No. ]:
57683-71-3

[ Name ]:
Methyl 2-sulfamoylbenzoate

[Synonym ]:
2-Aminosulfonyl-benzoic acid methyl ester
Methyl 2-sulfamoylbenzoate
o-Carbomethoxybenzene sufonamide
MFCD00009808
Benzoic acid, 2-(aminosulfonyl)-, methyl ester
2-Carbomethoxybenzenesulfonamide
EINECS 260-903-2

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
401.4±47.0 °C at 760 mmHg

[ Melting Point ]:
126-128 °C(lit.)

[ Molecular Formula ]:
C8H9NO4S

[ Molecular Weight ]:
215.226

[ Flash Point ]:
196.6±29.3 °C

[ Exact Mass ]:
215.025223

[ PSA ]:
94.84000

[ LogP ]:
0.30

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.557

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DH6830000
CHEMICAL NAME :
Benzoic acid, 2-sulfamoyl-, methyl ester
CAS REGISTRY NUMBER :
57683-71-3
BEILSTEIN REFERENCE NO. :
2728611
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C8-H9-N-O4-S
MOLECULAR WEIGHT :
215.24
WISWESSER LINE NOTATION :
ZSWR BVO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Behavioral - ataxia Musculoskeletal - other changes
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 13,144,1979

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
DH6830000

[ HS Code ]:
2935009090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • methyl 2-chlorosulfonylbenzoate
  • Methanol
  • Saccharin
  • Benzoic acid,2-(aminosulfonyl)-

DownStream

  • 2-(hydrazinecarbonyl)benzenesulfonamide
  • 3-methyl-1,2-benzothiazole 1,1-dioxide
  • Methyl 2-[(oxomethylene)sulfamoyl]benzoate
  • DesMethyl Methoxy Metsulfuron-Methyl
  • methyl 2-azidosulfonylbenzoate
  • 3-Phenylbenzo[D]Isothiazole 1,1-Dioxide
  • 3-ethyl-1,2-benzothiazole 1,1-dioxide

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

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Related Compounds

  • methyl 2-bromo-5-sulfamoylbenzoate
  • Methyl 2-Methoxy-5-Sulfamoylbenzoate
  • methyl 2-chloro-5-sulfamoylbenzoate
  • Methyl 2,4-dichloro-5-sulfamoylbenzoate
  • methyl 2-morpholin-4-yl-5-sulfamoylbenzoate
  • methyl 2,3-dimethoxy-5-sulphamoylbenzoate