Nisoxetine hydrochloride

Names

[ CAS No. ]:
57754-86-6

[ Name ]:
Nisoxetine hydrochloride

[Synonym ]:
MFCD00153850

Chemical & Physical Properties

[ Density]:
1.054g/cm3

[ Boiling Point ]:
404.8ºC at 760mmHg

[ Molecular Formula ]:
C₁₇H₂₂ClNO₂

[ Molecular Weight ]:
307.81500

[ Flash Point ]:
170.6ºC

[ Exact Mass ]:
307.13400

[ PSA ]:
30.49000

[ LogP ]:
4.61770

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2930909090

Customs

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Serotonergic signalling suppresses ataxin 3 aggregation and neurotoxicity in animal models of Machado-Joseph disease.

Brain 138 , 3221-37, (2015)

Polyglutamine diseases are a class of dominantly inherited neurodegenerative disorders for which there is no effective treatment. Here we provide evidence that activation of serotonergic signalling is...

The pro-inflammatory cytokine TNF-α regulates the activity and expression of the serotonin transporter (SERT) in astrocytes.

Neurochem. Res. 38(4) , 694-704, (2013)

Pro-inflammatory cytokines have been implicated in the precipitation of depression and related disorders, and the antidepressant sensitive serotonin transporter (SERT) may be a major target for immune...

Plasma membrane monoamine transporters: structure, regulation and function.

Nat. Rev. Neurosci. 4 , 13-25, (2003)