TBBz

Names

[ CAS No. ]:
577779-57-8

[ Name ]:
TBBz

[Synonym ]:
4,5,6,7-Tetrabrom-1H-benzimidazol
4,5,6,7-tetrabromobenzimidazole
2oxy
TBBz

Chemical & Physical Properties

[ Melting Point ]:
330-332ºC

[ Molecular Formula ]:
C₇H₂Br₄N₂

[ Molecular Weight ]:
433.72000

[ Exact Mass ]:
429.69500

[ PSA ]:
28.68000

[ LogP ]:
4.61290

MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H319

[ Precautionary Statements ]:
P301 + P310-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ RIDADR ]:
UN 2811 6.1 / PGIII

Precursor & DownStream

Precursor

DownStream

Articles

An unbiased evaluation of CK2 inhibitors by chemoproteomics: characterization of inhibitor effects on CK2 and identification of novel inhibitor targets.

Mol. Cell. Proteomics 7(6) , 1077-88, (2008)

Recently protein kinases have emerged as some of the most promising drug targets; and therefore, pharmaceutical strategies have been developed to inhibit kinases in the treatment of a variety of disea...

Casein kinase II contributes to the synergistic effects of BMP7 and BDNF on Smad 1/5/8 phosphorylation in septal neurons under hypoglycemic stress.

J. Neurochem. 109(3) , 733-43, (2009)

The combination of bone morphogenetic protein 7 (BMP7) and neurotrophins (e.g. brain-derived neurotrophic factor, BDNF) protects septal neurons during hypoglycemic stress. We investigated the signalin...

Characterizing the convergence of protein kinase CK2 and caspase-3 reveals isoform-specific phosphorylation of caspase-3 by CK2α': implications for pathological roles of CK2 in promoting cancer cell survival.

Oncotarget 4 , 560-71, (2013)

Protein kinase CK2 has emerged as a promising candidate for the treatment of a number of cancers. This enzyme is comprised of two catalytic subunits (CK2 and/or CK2α') that form complexes with homodim...

4-[1-(2-methoxyethyl)-1H-indol-3-yl]-N-(1-methyl-1H-pyrazol-3-yl)butanamide
2-[2-oxo-2-(1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)ethyl]-6-(2-thienyl)-3(2H)-pyridazinone
Methyl 2-{[(3-methyl-4-oxo-3,4-dihydrophthalazin-1-yl)acetyl]amino}-5-(2-methylpropyl)-1,3-thiazole-4-carboxylate
1-[(4-fluorophenyl)sulfonyl]-N-[2-(5-methoxy-1H-indol-1-yl)ethyl]-4-piperidinecarboxamide
N-cycloheptyl-3-(4-methoxyphenyl)-1-methyl-1H-pyrazole-5-carboxamide
N-(3,5-dimethoxyphenyl)-4-([1,2,4]triazolo[4,3-a]pyridin-3-yl)butanamide
6-phenyl-2-{[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]methyl}pyridazin-3(2H)-one
5-((2-(Methylsulfonyl)acetamido)methyl)thiophene-2-sulfonyl chloride
N-[2-(5-methoxy-1H-indol-1-yl)ethyl]-3-methyl-4-oxo-3,4-dihydro-1-phthalazinecarboxamide
3-(2,3-dihydro-1-benzofuran-5-yl)-N-{4-[(1,3,5-trimethyl-1H-pyrazol-4-yl)methyl]phenyl}propanamide

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