Acridine, 1-amino-

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Names

[ CAS No. ]:
578-06-3

[ Name ]:
Acridine, 1-amino-

[Synonym ]:
acridinamine
1-Aminoacridin
amino-acridine
1-AMINOACRIDINE
Acridin-1-amine
acridineamine
acridin-1-ylamine
1-Acridinamine

Chemical & Physical Properties

[ Molecular Formula ]:
C13H10N2

[ Molecular Weight ]:
194.23200

[ Exact Mass ]:
194.08400

[ PSA ]:
38.91000

[ LogP ]:
3.55140

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AR7200000
CHEMICAL NAME :
Acridine, 1-amino-
CAS REGISTRY NUMBER :
578-06-3
BEILSTEIN REFERENCE NO. :
0141124
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C13-H10-N2
MOLECULAR WEIGHT :
194.25
WISWESSER LINE NOTATION :
T C666 BNJ GZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
330 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Microorganism - not otherwise specified
DOSE/DURATION :
132 mg/L
REFERENCE :
JMOBAK Journal of Molecular Biology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,762,1961

Synthetic Route

Precursor & DownStream

Precursor

  • 1-amino-10H-acridin-9-one
  • 1-nitroacridine
  • 1-Nitroacridone
  • 2-acetylamino-6-anilino-benzoic acid
  • 2-acetamido-6-chlorobenzoic acid
  • Acridine

DownStream

  • N-acridin-1-ylacetamide
  • 1-Acridinol

Related Compounds

  • Acridine 1,2-oxide
  • cbz-1-amino-1-cyclodecanecarboxylic acid
  • 2-[1-AMINO-2-(2,4-DICHLOROPHENOXY)ETHYLIDENE]MALONONITRILE
  • (2S)-1-Amino-1-thioxo-2-propanyl acetate
  • 4-[(1-amino-9,10-dihydro-4-hydroxy-9,10-dioxo-2-anthryl)oxy]phenyl ethyl carbonate
  • disodium 1-amino-4-[(3-amino-2-methyl-5-sulphonatophenyl)amino]-9,10-dihydro-9,10-dioxoanthracene-2-sulphonate
  • 6-Acetyl-1,6-diazatetracyclo[7.6.1.0{5,16}.0{10,15}]hexadeca-9(16),10(15),11,13-tetraen-2-one
  • 8-bromo-2-methyl-3-phenyl-2,3,5,6-tetrahydro-4H-2,6-methano-1,3,5-benzoxadiazocine-4-thione
  • 3-(3,4-dimethylphenyl)-2-methyl-5,6-dihydro-2H-2,6-methanobenzo[g][1,3,5]oxadiazocine-4(3H)-thione
  • 8-bromo-3-(3,4-dimethylphenyl)-2-methyl-5,6-dihydro-2H-2,6-methanobenzo[g][1,3,5]oxadiazocine-4(3H)-thione
  • 8-chloro-3-(3,4-dimethylphenyl)-2-methyl-5,6-dihydro-2H-2,6-methanobenzo[g][1,3,5]oxadiazocine-4(3H)-thione
  • 3-(3,4-dimethylphenyl)-10-methoxy-2-methyl-5,6-dihydro-2H-2,6-methanobenzo[g][1,3,5]oxadiazocine-4(3H)-thione
  • 3-(3,5-dimethylphenyl)-2-methyl-5,6-dihydro-2H-2,6-methanobenzo[g][1,3,5]oxadiazocine-4(3H)-thione
  • 8-bromo-3-(3,5-dimethylphenyl)-2-methyl-5,6-dihydro-2H-2,6-methanobenzo[g][1,3,5]oxadiazocine-4(3H)-thione
  • [8-(3-Chlorophenyl)-4,7-dimethylpyrazolo[5,1-c][1,2,4]triazin-3-yl]-4-morpholinylmethanone
  • Methyl 8-(3-chlorophenyl)-7-ethyl-4-methylpyrazolo[5,1-c][1,2,4]triazine-3-carboxylate
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