Acridine, 1-amino-

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Names

[ CAS No. ]:
578-06-3

[ Name ]:
Acridine, 1-amino-

[Synonym ]:
acridinamine
1-Aminoacridin
amino-acridine
1-AMINOACRIDINE
Acridin-1-amine
acridineamine
acridin-1-ylamine
1-Acridinamine

Chemical & Physical Properties

[ Molecular Formula ]:
C13H10N2

[ Molecular Weight ]:
194.23200

[ Exact Mass ]:
194.08400

[ PSA ]:
38.91000

[ LogP ]:
3.55140

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AR7200000
CHEMICAL NAME :
Acridine, 1-amino-
CAS REGISTRY NUMBER :
578-06-3
BEILSTEIN REFERENCE NO. :
0141124
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C13-H10-N2
MOLECULAR WEIGHT :
194.25
WISWESSER LINE NOTATION :
T C666 BNJ GZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
330 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Microorganism - not otherwise specified
DOSE/DURATION :
132 mg/L
REFERENCE :
JMOBAK Journal of Molecular Biology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,762,1961

Synthetic Route

Precursor & DownStream

Precursor

  • 1-amino-10H-acridin-9-one
  • 1-nitroacridine
  • 1-Nitroacridone
  • 2-acetylamino-6-anilino-benzoic acid
  • 2-acetamido-6-chlorobenzoic acid
  • Acridine

DownStream

  • N-acridin-1-ylacetamide
  • 1-Acridinol

Related Compounds

  • Acridine 1,2-oxide
  • cbz-1-amino-1-cyclodecanecarboxylic acid
  • 2-[1-AMINO-2-(2,4-DICHLOROPHENOXY)ETHYLIDENE]MALONONITRILE
  • (2S)-1-Amino-1-thioxo-2-propanyl acetate
  • 4-[(1-amino-9,10-dihydro-4-hydroxy-9,10-dioxo-2-anthryl)oxy]phenyl ethyl carbonate
  • disodium 1-amino-4-[(3-amino-2-methyl-5-sulphonatophenyl)amino]-9,10-dihydro-9,10-dioxoanthracene-2-sulphonate
  • 5-{[(Benzyloxy)carbonyl]amino}-2-phenyl-1,3-oxazole-4-carboxylic acid
  • rac-methyl (3aR,5R,7aR)-octahydrofuro[3,2-b]pyridine-5-carboxylate
  • 1-(2-{[(benzyloxy)carbonyl]amino}cyclohexyl)-1H-1,2,3-triazole-4-carboxylic acid
  • 9-Azabicyclo[5.3.1]undecan-11-amine
  • 3-(Trifluoromethyl)bicyclo[1.1.1]pentane-1-sulfonamide
  • N-[(1-methyl-1H-imidazol-2-yl)methyl]-6-azaspiro[2.5]octan-1-amine
  • 2-Cyano-3-methylbutane-1-sulfonamide
  • 2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl) 5-methyl 1-methyl-1H-pyrrole-2,5-dicarboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 3,4-dihydro-1H-2-benzothiopyran-1-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 4-chlorothieno[2,3-c]pyridine-2-carboxylate
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