Diloxanide

Suppliers

Names

[ CAS No. ]:
579-38-4

[ Name ]:
Diloxanide

[Synonym ]:
Diloxanid
Amebamida
EINECS 209-439-4
Diloxanide
RD 3803
Acetamide,2,2-dichloro-N-(4-hydroxyphenyl)-N-methyl
Diloxanidum [INN-Latin]
Entamide
Ame-boots
Diloxanida [INN-Spanish]

Chemical & Physical Properties

[ Density]:
1.439g/cm3

[ Boiling Point ]:
356.2ºC at 760 mmHg

[ Melting Point ]:
175°

[ Molecular Formula ]:
C9H9Cl2NO2

[ Molecular Weight ]:
234.07900

[ Flash Point ]:
169.2ºC

[ Exact Mass ]:
233.00100

[ PSA ]:
40.54000

[ LogP ]:
2.15870

[ Index of Refraction ]:
1.615

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AE1970600
CHEMICAL NAME :
Acetanilide, 2,2-dichloro-4'-hydroxy-N-methyl-
CAS REGISTRY NUMBER :
579-38-4
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C9-H9-Cl2-N-O2
MOLECULAR WEIGHT :
234.09

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>12500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 18,128,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 18,128,1962

Precursor & DownStream

Precursor

DownStream

  • [4-[(2,2-dichloroacetyl)-methylamino]phenyl] 4-methylsulfonylbenzoate

Related Compounds

  • Diloxanide furoate
  • 1-(2-Methoxypyridin-4-yl)-4-[(1,3-oxazol-4-yl)methyl]piperazin-2-one
  • 1-[1-(4-Methylphthalazin-1-yl)piperidin-4-yl]pyrrolidin-3-ol
  • N,5-dimethyl-N-[1-(pyrazin-2-yl)azetidin-3-yl]thiophene-2-carboxamide
  • 6-[4-(2-Methoxypyridin-4-yl)-3-oxopiperazin-1-yl]pyridine-3-carbonitrile
  • 2-{[1-(5-Cyclopropyl-1,3,4-thiadiazol-2-yl)piperidin-4-yl]oxy}-5-ethylpyrimidine
  • 4-(Pyridine-2-carbonyl)-1-[2-(trifluoromethyl)pyridin-4-yl]piperazin-2-one
  • 4-(4-Methyl-1,3-thiazole-5-carbonyl)-1-[2-(trifluoromethyl)pyridin-4-yl]piperazin-2-one
  • 2-({1-[(6-Methylpyridin-2-yl)methyl]piperidin-3-yl}methoxy)pyridine-4-carbonitrile
  • 4-(1-methyl-1H-1,2,3-triazole-4-carbonyl)-1-[2-(trifluoromethyl)pyridin-4-yl]piperazin-2-one
  • N-[1-(3-Cyanopyrazin-2-yl)azetidin-3-yl]-N,5-dimethylthiophene-2-carboxamide
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