Bradykinin

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Names

[ CAS No. ]:
58-82-2

[ Name ]:
Bradykinin

[Synonym ]:
H-RPPGFSPFR-OH
Callidin I
RPPGFSPFR-OH
L-Arginine, L-arginyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-
BRADYZIDE
H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH
L-Arginyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-L-arginine
H-RPPGFSRPFR-OH
Callideic
N-(diaminomethylidene)-L-ornithyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-N-(diaminomethylidene)-L-ornithine
brs640
EINECS 227-781-2
prs640
BRADYKININ
RPPGFSPFR

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Melting Point ]:
170ºC

[ Molecular Formula ]:
C50H73N15O11

[ Molecular Weight ]:
1060.208

[ Exact Mass ]:
1059.561401

[ PSA ]:
413.78000

[ LogP ]:
-0.82

[ Index of Refraction ]:
1.693

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EE1530000
CHEMICAL NAME :
Bradykinin
CAS REGISTRY NUMBER :
58-82-2
LAST UPDATED :
199206
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C50-H73-N15-O11
MOLECULAR WEIGHT :
1060.38
WISWESSER LINE NOTATION :
T5NTJ AVYZ3MYZUM BV- AT5NTJ BVM1VMY1R&VMY1QV- AT5NTJ BVMY1R&VMYVQ3MYZUM

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
DOSE :
25 ug/kg
SEX/DURATION :
female 7-12 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
DOSE :
25 ug/kg
SEX/DURATION :
female 7-12 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - urogenital system

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - mouse Embryo
DOSE/DURATION :
500 ug/L
REFERENCE :
DANKAS Doklady Akademii Nauk SSSR. Proceedings of the Academy of Sciences of the USSR. For English translation, see DBIOAM and DKBSAS. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1933- Volume(issue)/page/year: 282,173,1985

Safety Information

[ Safety Phrases ]:
S22;S24/25

Precursor & DownStream

Precursor

DownStream

  • L-arginine
  • (Des-Arg9)-Bradykinin acetate salt
  • L-serine
  • L-Phenylalanine
  • Glycine
  • Proline

Related Compounds

  • Bradykinin
  • MK-bradykinin
  • 1-8-Bradykinin
  • Tyr-Bradykinin
  • Lys-Bradykinin
  • Bradykinin: 1-7
  • 2-(2-chlorophenyl)-N-(2-cyclohexyl-2-hydroxyethyl)acetamide
  • N-propyl-6-(1H-pyrazol-1-yl)pyridazine-3-carboxamide
  • N-(1H-indol-4-yl)-2-(1-oxophthalazin-2(1H)-yl)acetamide
  • 5-chloro-2-methoxy-N-(5-oxopyrrolidin-3-yl)benzamide
  • N-(2-hydroxy-2-phenylpropyl)-3-(trifluoromethyl)benzamide
  • Potassium 2-hydroxy-4-(3-nitrobenzenesulfonamido)benzoate
  • N-(5-oxopyrrolidin-3-yl)-3-(trifluoromethyl)benzamide
  • N-(5-oxopyrrolidin-3-yl)-1-naphthamide
  • 5-bromo-N-(5-oxopyrrolidin-3-yl)furan-2-carboxamide
  • N-(but-3-yn-1-yl)cyclohexanesulfonamide
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