Uridine

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Names

[ CAS No. ]:
58-96-8

[ Name ]:
Uridine

[Synonym ]:
1-β-δ-Ribofuranosyluracil
Uracil, 1-β-D-ribofuranosyl-
uracil riboside
EINECS 200-407-5
1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-2,4(1H,3H)-pyrimidinedione
URD
1-b-D-Ribofuranosyluracil
Uracil-1-β-D-ribofuranoside
1-b-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione
1-(β-D-Ribofuranosyl)pyrimidin-2,4(1H,3H)-dion
NFDB2
1-β-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione
Uridine
D-URIDINE
MFCD00006526
T6NVMVJ A- BT5OTJ CQ DQ E1Q &&β-D-Ribo Form
2(1H)-Pyrimidinone, 4-hydroxy-1-β-D-ribofuranosyl-
2,4(1H,3H)-pyrimidinedione, 1-β-D-ribofuranosyl-
4-Hydroxy-1-(β-D-ribofuranosyl)-2(1H)-pyrimidinone
Uridin
Diquafosol Impurity 11

Chemical & Physical Properties

[ Density]:
1.9±0.1 g/cm3

[ Boiling Point ]:
567.9±60.0 °C at 760 mmHg

[ Melting Point ]:
163-167 °C(lit.)

[ Molecular Formula ]:
C9H12N2O6

[ Molecular Weight ]:
244.201

[ Flash Point ]:
297.2±32.9 °C

[ Exact Mass ]:
244.069534

[ PSA ]:
124.78000

[ LogP ]:
-1.55

[ Vapour Pressure ]:
0.0±3.5 mmHg at 25°C

[ Index of Refraction ]:
1.732

[ Storage condition ]:
2~8°C

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YR1450000
CHEMICAL NAME :
Uracil, 1-beta-D-ribofuranosyl-
CAS REGISTRY NUMBER :
58-96-8
LAST UPDATED :
199701
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C9-H12-N2-O6
MOLECULAR WEIGHT :
244.23

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4335 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay)
TYPE OF TEST :
Micronucleus test

MUTATION DATA

TYPE OF TEST :
DNA damage
TEST SYSTEM :
Mammal - species unspecified Lymphocyte
DOSE/DURATION :
100 mmol/L
REFERENCE :
PNASA6 Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915- Volume(issue)/page/year: 48,686,1962 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1002 No. of Facilities: 35 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 115 (estimated) No. of Female Employees: 64 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
YR1450000

[ Packaging Group ]:
I; II; III

[ Hazard Class ]:
6.1

[ HS Code ]:
2934999090

Synthetic Route

Precursor & DownStream

Precursor

  • 2',3'-o-isopropylideneuridine
  • 5'-o-trityluridine
  • uridine triacetate
  • 3',5'-O-(1,1,3,3-TETRAISOPROPYL-1,3-DISILOXANEDIYL)URIDINE
  • 2′,3′-O-bis-(benzyloxycarbonyl)uridine
  • 3',5'-di(t-butyldimethylsilyl)-β-uridine
  • 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[[(4-methoxyphenyl)-diphenylmethoxy]methyl]oxolan-2-yl]pyrimidine-2,4-dione
  • Uridine,2',3'-O-(1-methylethylidene)-5'-O-(triphenylmethyl)-

DownStream

  • 2,2'-Cyclouridine
  • 1-β-D-Arabinofuranosyluracil
  • 2,2'-Anhydrouridine 3'-carbamate
  • Uridine, 3'-carbamate
  • Uridine, 2'-carbamate
  • 2',3'-o-isopropylideneuridine
  • D-Ribose
  • Uracil
  • Ribavirin

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Related Compounds

  • uridine
  • uridine
  • uridine3
  • AZURIDINE
  • L-Uridine
  • Uridine-d2
  • 4-iodo-2-(1H-1,2,3,4-tetrazol-1-yl)benzoic acid
  • Methyl 5-carbamimidoylpyridine-3-carboxylate hydrochloride
  • Methyl 6-chloro-3-(methylamino)-2-pyridinecarboxylate
  • 5-bromo-1H,1aH,6H,6aH-cyclopropa[a]inden-1-amine hydrochloride
  • 4-(Piperidin-3-yl)-2-(trifluoromethyl)pyridine
  • (2S,3S)-3-methyl-2-(trifluoromethyl)morpholine hydrochloride
  • [(1R,6R)-6-(trifluoromethyl)cyclohex-3-en-1-yl]methanamine hydrochloride
  • 3-Bromo-5-(5-imidazolyl)pyridine
  • 4-(5,6-Dichloropyridin-3-yl)-1,3-thiazol-2-amine
  • 1-(4-methyl-1H-imidazol-2-yl)cyclobutan-1-amine dihydrochloride
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