1,5,7-Triazabicyclo[4.4.0]dec-5-ene

Suppliers

Names

[ CAS No. ]:
5807-14-7

[ Name ]:
1,5,7-Triazabicyclo[4.4.0]dec-5-ene

[Synonym ]:
2H-Pyrimido[1,2-a]pyrimidine, 1,3,4,6,7,8-hexahydro-
MFCD00043003
1,3,4,6,7,8-hexahydropyrimido[1,2-a]pyrimidine
3,4,6,7,8,9-hexahydro-2h-pyrimido[1,2-a]pyrimidine
Triazabicyclodecene
EINECS 227-367-1
TBD
1,5,7-Triazabicyclo[4.4.0]dec-5-ene
1,3,4,6,7,8-hexahydro-2H-pyrimido(1,2-a)pyrimidine
1,3,4,6,7,8-Hexahydro-2H-pyrimido[1,2-a]pyrimidine
1,5,7-triazabicyclo-[4.4.0]dec-5-ene

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
222.3±23.0 °C at 760 mmHg

[ Melting Point ]:
125-130 °C(lit.)

[ Molecular Formula ]:
C7H13N3

[ Molecular Weight ]:
139.20

[ Flash Point ]:
88.3±22.6 °C

[ Exact Mass ]:
139.110947

[ PSA ]:
27.63000

[ LogP ]:
-1.08

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.656

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C: Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 1759 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2933599090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • bis(3-aminopropyl)amine
  • 1,3-DI-P-TOLYLCARBODIIMIDE
  • Guanidine hydrochloride
  • N,N′-diisopropylcarbodiimide
  • Dicyclohexylcarbodiimide
  • 1-(3-aminopropyl)tetrahydro-2(1H)-pyrimidinone
  • Cyanamide

DownStream

  • 2(1H)-Pyrimidinone,tetrahydro-5-hydroxy-
  • [12]anen3
  • Propoxybenzene
  • Butanol
  • 1-butyl-2,3,4,6,7,8-hexahydropyrimido[1,2-a]pyrimidine
  • nsc334066

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

A block copolymer of zwitterionic polyphosphoester and polylactic acid for drug delivery.

Biomater. Sci. 3 , 1105-13, (2015)

Polymeric nanoparticles have been widely used as nano-drug delivery systems in preclinical and clinical trials for cancer therapy, and these systems usually need to be sterically stabilized by poly(et...

Up-regulation of miR-21 and miR-23a Contributes to As2 O3 -induced hERG Channel Deficiency.

Basic Clin Pharmacol Toxicol. 116 , 516-23, (2015)

Arsenic trioxide (As2O3) is used to treat acute pro-myelocytic leukaemia. However, the cardiotoxicity of long QT syndrome restricts its clinical application. Previous studies showed that As2O3 can dam...

Peroxiredoxin 2 is involved in vasculogenic mimicry formation by targeting VEGFR2 activation in colorectal cancer.

Med. Oncol. 32(1) , 414, (2014)

The mammalian peroxiredoxin 2 (Prdx2) is a member of thiol-dependent antioxidant proteins and plays an important role in the progression of colorectal cancer (CRC). The aim of this study was to confir...


More Articles

Related Compounds

  • 7-butyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene
  • 7-Methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene
  • 7-formyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene
  • 7-propan-2-yl-1,5,7-triazabicyclo[4.4.0]dec-5-ene
  • 2-(9-Oxoxanthen-2-yl)propionic Acid 1,5,7-Triazabicyclo[4.4.0]dec-5-ene Salt
  • MTBD dodecyl bromide quat