α-MSH trifluoroacetate salt

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Names

[ CAS No. ]:
581-05-5

[ Name ]:
α-MSH trifluoroacetate salt

[Synonym ]:
N-Acetyl-L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valinamide
α-Melanocyte Stimulating Hormone
MFCD00133062
L-Valinamide, N-acetyl-L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-
α-MSH

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Molecular Formula ]:
C₇₇H₁₀₉N₂₁O₁₉S

[ Molecular Weight ]:
1664.884

[ Exact Mass ]:
1663.792969

[ PSA ]:
668.28000

[ LogP ]:
-1.77

[ Index of Refraction ]:
1.682

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
Soluble in water (~1 mg/ml).

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
N

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Triterpene glycosides and other polar constituents of shea (Vitellaria paradoxa) kernels and their bioactivities.

Phytochemistry 108 , 157-70, (2014)

The MeOH extract of defatted shea (Vitellaria paradoxa; Sapotaceae) kernels was investigated for its constituents, and fifteen oleanane-type triterpene acids and glycosides, two steroid glucosides, tw...

Reduced melanocortin production causes sexual dysfunction in male mice with POMC neuronal insulin and leptin insensitivity.

Endocrinology 156(4) , 1372-85, (2015)

Proopiomelanocortin (POMC)-derived peptides like α-melanocyte-stimulating hormone (MSH) substantially improve hepatic insulin sensitivity and regulate energy expenditure. Melanocortinergic agents are ...

Effect of barodenervation on cardiovascular responses elicited from the hypothalamic arcuate nucleus of the rat.

PLoS ONE 7(12) , e53111, (2012)

We have previously reported that chemical stimulation of the hypothalamic arcuate nucleus (ARCN) in the rat elicited increases as well as decreases in blood pressure (BP) and sympathetic nerve activit...

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