DEBRISOQUIN SULFATE
Suppliers
Names
[ CAS No. ]:
581-88-4
[ Name ]:
DEBRISOQUIN SULFATE
[Synonym ]:
2(1H)-Isoquinolinecarboximidamide, 3,4-dihydro-, sulfate (2:1)
Debrisoquin hemisulfate
Bis[3,4-dihydroisoquinolin-2(1H)-yl(imino)methanaminium] sulfate
debrisoquine sulfate
3,4-Dihydroisoquinoline-2(1H)-carboximidamide sulfate (2:1)
3,4-Dihydro-2(1H)-isoquinolinecarboximidamide sulfate (2:1)
Debrisoquin sulfate
debrisoquine sulphate
Chemical & Physical Properties
[ Boiling Point ]:
309.8ºC at 760 mmHg
[ Melting Point ]:
278-280°, 284-285° or 266-268° (H2O)
[ Molecular Formula ]:
C10H13N3.1/2H2O4S
[ Molecular Weight ]:
224.27
[ Flash Point ]:
141.1ºC
[ Exact Mass ]:
448.189270
[ PSA ]:
189.20000
[ LogP ]:
3.78020
[ Storage condition ]:
-20°C Freezer
[ Water Solubility ]:
H2O: 20 mg/mL with heat
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NW7010000
- CAS REGISTRY NUMBER :
- 581-88-4
- LAST UPDATED :
- 198804
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C10-H13-N3.1/2H2-O4-S
- MOLECULAR WEIGHT :
- 224.30
- WISWESSER LINE NOTATION :
- T66 CNT&J CYZUM & 2WSQQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 610 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Lungs, Thorax, or Respiration - respiratory depression Nutritional and Gross Metabolic - body temperature decrease
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 17,129,1979
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 235 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CTCEA9 Current Therapeutic Research, Clinical & Experimental. (Therapeutic Research Press, Inc., POB 514, Tenafly, NJ 07670) V.1- 1959- Volume(issue)/page/year: 6,299,1964
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 132 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CTCEA9 Current Therapeutic Research, Clinical & Experimental. (Therapeutic Research Press, Inc., POB 514, Tenafly, NJ 07670) V.1- 1959- Volume(issue)/page/year: 6,299,1964
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 136 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CTCEA9 Current Therapeutic Research, Clinical & Experimental. (Therapeutic Research Press, Inc., POB 514, Tenafly, NJ 07670) V.1- 1959- Volume(issue)/page/year: 6,299,1964
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 31700 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CTCEA9 Current Therapeutic Research, Clinical & Experimental. (Therapeutic Research Press, Inc., POB 514, Tenafly, NJ 07670) V.1- 1959- Volume(issue)/page/year: 6,299,1964
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
22
[ Safety Phrases ]:
26-36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
NW7010000
[ HS Code ]:
2933499090
Customs
[ HS Code ]: 2933499090
[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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