2-bromohydroquinone

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Names

[ CAS No. ]:
583-69-7

[ Name ]:
2-bromohydroquinone

[Synonym ]:
2-Bromo-1,4-benzenediol
2-bromobenzene-1,4-diol
EINECS 209-516-2
2-bromohydroquinone
MFCD00041747
1,4-Benzenediol, 2-bromo-

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Boiling Point ]:
278.3±20.0 °C at 760 mmHg

[ Melting Point ]:
112-116 °C(lit.)

[ Molecular Formula ]:
C6H5BrO2

[ Molecular Weight ]:
189.007

[ Flash Point ]:
122.1±21.8 °C

[ Exact Mass ]:
187.947281

[ PSA ]:
40.46000

[ LogP ]:
2.01

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.657

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CZ8920000
CHEMICAL NAME :
1,4-Benzenediol, 2-bromo-
CAS REGISTRY NUMBER :
583-69-7
BEILSTEIN REFERENCE NO. :
2042870
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C6-H5-Br-O2
MOLECULAR WEIGHT :
189.02

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
87200 ug/kg
SEX/DURATION :
female 9 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 120,1,1993

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
CZ8920000

[ HS Code ]:
2908199090

Precursor & DownStream

Precursor

DownStream

  • 2,5-DIHYDROXY-4'-METHYLBIPHENYL
  • 2-BROMO-1,4-BENZOQUINONE
  • 2,3,5,6-Tetrabromo-1,4-benzoquinone
  • 2-methylsulfanylbenzene-1,4-diol
  • Hydroquinone
  • 2,3,5-tribromocyclohexa-2,5-diene-1,4-dione
  • 4-(Benzyloxy)-3-bromophenol
  • 1-Bromo-2,5-dimethoxybenzene
  • 10-(2,5-Dihydroxyphenyl)-10H-9-Oxa-10-Phospha-Phenantbrene-10-Oxide
  • 1,4-Cyclohexanediol

Customs

[ HS Code ]: 2908199090

[ Summary ]:
HS: 2908199090. derivatives of polyphenols or phenol-alcohols containing only halogen substituents and their salts. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tariff:5.5%. general tariff:30.0%

Articles

Dihydroxylated mercapturic acid metabolites of bromobenzene.

Chem. Res. Toxicol. 5(4) , 561-7, (1992)

Bromobenzene is metabolized to electrophilic epoxides and quinones which covalently bind to protein sulfur nucleophiles, yet no quinone-derived mercapturic acid metabolites of bromobenzene have been r...

Inhibition of respiration in rabbit proximal tubules by bromophenols and 2-bromohydroquinone.

Adv. Exp. Med. Biol. 197 , 911-7, (1986)

Cellular toxicity of bromobenzene and bromobenzene metabolites to rabbit proximal tubules: the role and mechanism of 2-bromohydroquinone.

J. Pharmacol. Exp. Ther. 237(2) , 456-61, (1986)

An in vitro model using a suspension of rabbit renal proximal tubules was developed to investigate the mechanism of nephrotoxicity of bromobenzene. Using oxygen consumption, glutathione concentrations...


More Articles

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