Benzamide,4-amino-N-(2-aminophenyl)-

Suppliers

Names

[ Name ]:
Benzamide,4-amino-N-(2-aminophenyl)-

[Synonym ]:
Goe-1734
4-Amino-N-(2'-aminophenyl)-benzamide
Dinaline [INN]
Dinalina [Spanish]
2',4-Diaminobenzanilide
Dinaline [French]
2',4-Diaminobenzanilid
Dinaline
Dianiline
Dinalinum [Latin]

Chemical & Physical Properties

[ Density]:
1.314g/cm3

[ Boiling Point ]:
367.2ºC at 760mmHg

[ Molecular Formula ]:
C₁₃H₁₃N₃O

[ Molecular Weight ]:
227.26200

[ Flash Point ]:
175.9ºC

[ Exact Mass ]:
227.10600

[ PSA ]:
81.14000

[ LogP ]:
3.33870

[ Index of Refraction ]:
1.734

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CU8994000

CHEMICAL NAME :: Benzamide, 4-amino-N-(2-aminophenyl)-

CAS REGISTRY NUMBER :: 58338-59-3

LAST UPDATED :: 199612

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C13-H13-N3-O

MOLECULAR WEIGHT :: 227.29

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 95 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 625 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 630 mg/kg/6W-I

TOXIC EFFECTS :: Blood - changes in bone marrow (not otherwise specified) Blood - changes in erythrocyte (RBC) count Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 462 mg/kg/14W-I

TOXIC EFFECTS :: Blood - changes in bone marrow (not otherwise specified)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 6678 mg/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Endocrine - adrenal cortex tumors Reproductive - Maternal Effects - uterus, cervix, vagina

MUTATION DATA

TEST SYSTEM :: Rodent - rat

DOSE/DURATION :: 10 mg/kg

REFERENCE :: CTRRDO Cancer Treatment Reports. (Washington, DC) V.60-71, 1976-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 69,1415,1985

Precursor & DownStream

Precursor

DownStream

Benzenamine,4-(1H-benzimidazol-2-yl)-
4-Aminobenzoic acid
o-Phenylenediamine

Related Compounds

Benzamide, 4-amino-N-2-(4-methyl-1-piperazinyl)ethyl-
Benzamide,4-amino-N-(2-thienylmethyl)-
Benzamide,4-amino-N-2-phenanthrenyl-
Benzamide,4-amino-N-[(2,3,6,7-tetrahydro-1,3,7-trimethyl-2,6-dioxo-1H-purin-8-yl)methyl]-
N-iso-butyl-4-aminobenzamide
procainamide
Olean-12-en-28-oic acid, 3-[(O-6-deoxy-I+/--L-mannopyranosyl-(1a4)-O-I(2)-D-glucopyranosyl-(1a6)-I(2)-D-glucopyranosyl)oxy]-, (3I(2))-
4-Amino-5-hydroxy-3,6-bis[(1E)-2-[2-methoxy-4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]diazenyl]-2,7-naphthalenedisulfonic acid
ethyl 2-(4-amino-5-methyl-1H-pyrazol-1-yl)propanoate
1-[3-chloro-4-(4-methanesulfonyl-1H-pyrazol-1-yl)phenyl]ethan-1-amine
tert-butyl (2E)-3-[2-(trifluoromethoxy)phenyl]prop-2-enoate
1-(3-amino-4-methyl-1H-pyrazol-1-yl)-3-(dimethylamino)propan-2-ol
{3-[4-(3,4-dimethoxyphenyl)-1H-1,2,3-triazol-1-yl]phenyl}methanol
4-amino-3-(2,3-dihydro-1-benzofuran-5-yl)-N-ethylbutanamide
2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)methyl]benzoic acid
2-(1-{[(9H-fluoren-9-yl)methoxy]carbonyl}pyrrolidin-2-yl)propanoic acid

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.