1,2-butanediol

Suppliers

Names

[ CAS No. ]:
584-03-2

[ Name ]:
1,2-butanediol

[Synonym ]:
1,2-Dihydroxybutane
EINECS 209-527-2
Butanediol, 1,2-
1,2-(Dihydroxy)butane
MFCD00004570
±-1,2-Butanediol
1,2-butanediol
1,2-butylene glycol
1,2-Butanediol, (±)-
butane-1,2-diol
methylpropyldiol
UNII:RUN0H01QEU

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
190.3±8.0 °C at 760 mmHg

[ Melting Point ]:
-50 °C

[ Molecular Formula ]:
C4H10O2

[ Molecular Weight ]:
90.121

[ Flash Point ]:
93.3±0.0 °C

[ Exact Mass ]:
90.068077

[ PSA ]:
40.46000

[ LogP ]:
-0.81

[ Vapour Pressure ]:
0.1±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.438

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EK0380000
CHEMICAL NAME :
1,2-Butanediol
CAS REGISTRY NUMBER :
584-03-2
BEILSTEIN REFERENCE NO. :
0969169
LAST UPDATED :
199709
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C4-H10-O2
MOLECULAR WEIGHT :
90.14
WISWESSER LINE NOTATION :
QY2&1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
16 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,207,1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4192 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 49,385,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7923 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1822 (estimated) No. of Female Employees: 272 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S24/25

[ WGK Germany ]:
2

[ RTECS ]:
EK0380000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-butene-1,2-diol
  • Glycerol
  • 1-HYDROXY-2-BUTANONE
  • (S)-3-Butene-1,2-diol
  • 1,2-EPOXYBUTANE
  • Cellulose microcrystalline
  • Sorbitol
  • 1,4-Butanediol
  • Carbon dioxide
  • carbon monoxide

DownStream

  • (S)-2-Hydroxybutyric acid
  • 2-Ethylbenzofuran
  • 2-hydroxybutyl nitrate
  • 1-hydroxybutan-2-yl nitrate
  • (R)-2-FLUOROMANDELICACID
  • 1-(Benzyloxy)-2-butanol
  • 2-benzyloxybutanol
  • 1,2-Butylene Carbonate
  • 1-HYDROXY-2-BUTANONE
  • 2-Oxobutanal

Articles

Analysis of eight glycols in serum using LC-ESI-MS-MS.

J. Anal. Toxicol. 38(9) , 676-80, (2014)

A liquid chromatography coupled with electrospray tandem mass spectrometry method was developed for the analysis of ethylene glycol, diethylene glycol, triethylene glycol, 1,4-butanediol, 1,2-butanedi...

Efficient conversion of 1,2-butanediol to (R)-2-hydroxybutyric acid using whole cells of Gluconobacter oxydans.

Bioresour. Technol. 115 , 75-8, (2012)

(R)-2-Hydroxybutyric acid ((R)-2-HBA) is an important building block for azinothricin family of antitumour antibiotics and biodegradable poly(2-hydroxybutyric acid). However, optically active (R)-2-HB...

Simultaneous extraction of flavonoids from Chamaecyparis obtusa using deep eutectic solvents as additives of conventional extractions solvents.

J. Chromatogr. Sci. 53 , 836-40, (2015)

Three flavones (quercetin, myricetin and amentoflavone) were extracted from Chamaecyparis obtusa leaves using deep eutectic solvents (DESs) as additives to conventional extractions solvents. Sixteen D...


More Articles

Related Compounds

  • 1,2-butanediol
  • 1,2-butanediol
  • 1,2-butanediol
  • (R)-(+)-1,2-BUTANEDIOL
  • 4-bromo-1,2-butanediol
  • 1-Phenyl-1,2-butanediol
  • 3-(Dispiro[2.0.24.13]heptan-7-yl)propiolic acid
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • Ethyl 3-chloro-2-methyl-5-nitrophenylacetic acid
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 1,2-Dichloroethane-1-sulfinyl chloride
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde