5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinoline

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Names

[ CAS No. ]:
5840-01-7

[ Name ]:
5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinoline

[Synonym ]:
5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinoline
4H-Pyrrolo[3,2,1-ij]quinoline, 5,6-dihydro-
Lilolidine

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
318.4±11.0 °C at 760 mmHg

[ Melting Point ]:
86.5-88ºC

[ Molecular Formula ]:
C11H11N

[ Molecular Weight ]:
157.212

[ Flash Point ]:
146.3±19.3 °C

[ Exact Mass ]:
157.089142

[ PSA ]:
4.93000

[ LogP ]:
3.12

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.656

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinoline-1-carboxylic acid
  • 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline 1,2-dicarboxylic acid
  • leucoline
  • Ethylene glycol
  • 5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinoline-2-carboxylic acid
  • 1,2,3,4-Tetrahydroquinoline
  • Ethyl 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline-1-carboxylate
  • ethyl 3-(3,4-dihydro-2H-quinolin-1-yl)-2-oxo-propanoate

DownStream

  • Tivantinib (ARQ 197)
  • Methyl 2-(5,6-Dihydro-4H-Pyrrolo[3,2,1-Ij]Quinolin-1-Yl)-2-Oxoacetate
  • 3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrole-2,5-dione
  • 1,2,5,6-Tetrahydro-4H-pyrrolo(3,2,1-ij)quinoline

Related Compounds

  • 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline-1,2-dione
  • 1,2-Dimethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline
  • 5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinoline-1-carboxylic acid
  • 5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinoline-2-carboxylic acid
  • 8-Nitro-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline-1,2-dione
  • Ethyl 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline-1-carboxylate
  • rac-(1R,2S)-2-[({1-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]spiro[2.3]hexan-1-yl}formamido)methyl]cyclopropane-1-carboxylic acid
  • 3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-({7-oxaspiro[3.5]nonan-2-yl}carbamoyl)propanoic acid
  • 2-({2-[5-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pyridin-2-yl]-N-methylacetamido}oxy)acetic acid
  • 2-({1-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5-fluorophenyl]-N-methylformamido}oxy)acetic acid
  • 2-({1-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-fluorophenyl]-N-methylformamido}oxy)acetic acid
  • 2-[(1-{1-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)ethyl]-1H-imidazol-4-yl}-N-methylformamido)oxy]acetic acid
  • 2-({1-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)bicyclo[2.2.1]heptan-2-yl]-N-methylformamido}oxy)acetic acid
  • 2-({2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclohexyl]-N-methylacetamido}oxy)acetic acid
  • 2-[(1-{4-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexyl}-N-methylformamido)oxy]acetic acid
  • 2-({1-[1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylcyclohexyl]-N-methylformamido}oxy)acetic acid
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