5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinoline

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Names

[ CAS No. ]:
5840-01-7

[ Name ]:
5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinoline

[Synonym ]:
5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinoline
4H-Pyrrolo[3,2,1-ij]quinoline, 5,6-dihydro-
Lilolidine

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
318.4±11.0 °C at 760 mmHg

[ Melting Point ]:
86.5-88ºC

[ Molecular Formula ]:
C11H11N

[ Molecular Weight ]:
157.212

[ Flash Point ]:
146.3±19.3 °C

[ Exact Mass ]:
157.089142

[ PSA ]:
4.93000

[ LogP ]:
3.12

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.656

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinoline-1-carboxylic acid
  • 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline 1,2-dicarboxylic acid
  • leucoline
  • Ethylene glycol
  • 5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinoline-2-carboxylic acid
  • 1,2,3,4-Tetrahydroquinoline
  • Ethyl 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline-1-carboxylate
  • ethyl 3-(3,4-dihydro-2H-quinolin-1-yl)-2-oxo-propanoate

DownStream

  • Tivantinib (ARQ 197)
  • Methyl 2-(5,6-Dihydro-4H-Pyrrolo[3,2,1-Ij]Quinolin-1-Yl)-2-Oxoacetate
  • 3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrole-2,5-dione
  • 1,2,5,6-Tetrahydro-4H-pyrrolo(3,2,1-ij)quinoline

Related Compounds

  • 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline-1,2-dione
  • 1,2-Dimethyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline
  • 5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinoline-1-carboxylic acid
  • 5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinoline-2-carboxylic acid
  • 8-Nitro-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline-1,2-dione
  • Ethyl 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline-1-carboxylate
  • (3-(2,2-Difluoroethyl)-3-methylcyclobutyl)methanamine
  • 1-(4-Chloro-1-benzothiophen-3-yl)methanamine hydrochloride
  • {[3-Cyclopropyl-5-(difluoromethyl)phenyl]methyl}(methyl)amine
  • tert-butyl 4-[(4-methoxypiperidin-4-yl)methyl]-1H-imidazole-1-carboxylate
  • 3-Cyclopropyl-5-(difluoromethyl)benzaldehyde
  • 2-(3-{[(Tert-butoxy)carbonyl]amino}-4-hydroxy-5-methoxyphenyl)-2-methylpropanoic acid
  • {[3-(2,2-Difluoroethyl)-3-methylcyclobutyl]methyl}(methyl)amine
  • 1-[3-(Prop-2-yn-1-yl)phenyl]methanamine
  • tert-butyl N-(2,3-dimethyl-1-oxo-4-phenylbut-3-en-2-yl)-N-methylcarbamate
  • Dimethyl[4-(piperidin-4-yloxy)but-2-yn-1-yl]amine
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