Cephaeline Dihydrochloride
Suppliers
Names
[ CAS No. ]:
5853-29-2
[ Name ]:
Cephaeline Dihydrochloride
[Synonym ]:
10,11,7'-Trimethoxy-emetan-6'-ol,Hydrochlorid
cephaeline dihydrochloride
10,11,7'-trimethoxy-emet-1'-ene-9,6'-diol
Alangicine
10,11,7'-trimethoxy-emetan-6'-ol,dihydrochloride
10,11,7'-Trimethoxy-emetan-6'-ol,Dihydrochlorid
EINECS 227-463-3
(-)-Cephaeline (dihydrochloride)
Chemical & Physical Properties
[ Molecular Formula ]:
C28H40Cl2N2O4
[ Molecular Weight ]:
539.53
[ PSA ]:
63.19000
[ LogP ]:
5.70910
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- FJ9450000
- CHEMICAL NAME :
- Cephaeline hydrochloride
- CAS REGISTRY NUMBER :
- 5853-29-2
- LAST UPDATED :
- 199206
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C28-H38-N2-O4.2Cl-H
- MOLECULAR WEIGHT :
- 539.60
- WISWESSER LINE NOTATION :
- T B666 GNTT&J E2 LO1 MO1 D1- BT66 CMT&J HQ IO1 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 104,421,1952
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 6500 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 10,73,1917/1918
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 74970 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. (Bethesda, MD 20205) Volume(issue)/page/year: JAN1986
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 20530 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. (Bethesda, MD 20205) Volume(issue)/page/year: JAN1986
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 8 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 10,73,1917/1918
Safety Information
[ RIDADR ]:
1544
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)