Alanosine

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Names

[ CAS No. ]:
5854-93-3

[ Name ]:
Alanosine

[Synonym ]:
SDX-102
L-Alanine, 3-(hydroxynitrosoamino)-
L-2-Amino-3-[(N-nitroso)hydroxylamino]propionic acid
alanosine
L-2-Amino-3-(hydroxynitrosoamino)propanoic Acid
3-[Hydroxy(nitroso)amino]-L-alanine
SDX 102
L-alanosine
L-Alanine, 3- (hydroxynitrosoamino)-

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Boiling Point ]:
366.9±52.0 °C at 760 mmHg

[ Melting Point ]:
190ºC (dec.)

[ Molecular Formula ]:
C3H7N3O4

[ Molecular Weight ]:
149.105

[ Flash Point ]:
175.7±30.7 °C

[ Exact Mass ]:
149.043655

[ PSA ]:
116.22000

[ LogP ]:
-0.56

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.616

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UE6490000
CHEMICAL NAME :
Propionic acid, 2-amino-3-(hydroxynitrosamino)-, (L)-
CAS REGISTRY NUMBER :
5854-93-3
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C3-H7-N3-O4
MOLECULAR WEIGHT :
149.13
WISWESSER LINE NOTATION :
QVYZ1NQNO -L

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3676490
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
845 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. (Bethesda, MD 20205) Volume(issue)/page/year: JAN1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3676490

Precursor & DownStream

Precursor

  • 3-[Nitroso(benzyloxy)amino]-N-[(benzyloxy)carbonyl]-L-alanine
  • L-2-Amino-3-hydroxylamino-propionsaeure

DownStream

Related Compounds

  • DL-Alanosine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 4-(2-chlorophenyl)-6-methyl-3,4,6,7-tetrahydro-1H-pyrrolo[3,4-d]pyrimidine-2,5-dione
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide