Dyclonine

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Names

[ CAS No. ]:
586-60-7

[ Name ]:
Dyclonine

[Synonym ]:
Dyclocainum
1-(4-butoxyphenyl)-3-piperidin-1-ylpropan-1-one
4'-Butoxy-3-N-piperidino-propiophenon,Dyclon
Diclonina [INN-Spanish]
1-(4-butoxy-phenyl)-3-piperidin-1-yl-propan-1-one
1-(4-butoxyphenyl)-3-(1-piperidinyl)-1-propanone
Dycloninum
Diclonia
Dyclonin
Diclonina
Dyclocaine
Dycloninum [INN-Latin]
Dyclonine [INN:BAN]

Chemical & Physical Properties

[ Density]:
1.017g/cm3

[ Boiling Point ]:
424.5ºC at 760 mmHg

[ Molecular Formula ]:
C₁₈H₂₇NO₂

[ Molecular Weight ]:
289.41200

[ Flash Point ]:
210.5ºC

[ Exact Mass ]:
289.20400

[ PSA ]:
29.54000

[ LogP ]:
3.86210

[ Index of Refraction ]:
1.517

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UG8672500

CHEMICAL NAME :: Propiophenone, 4'-butoxy-3-piperidino-

CAS REGISTRY NUMBER :: 586-60-7

BEILSTEIN REFERENCE NO. :: 0224037

LAST UPDATED :: 199709

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C18-H27-N-O2

MOLECULAR WEIGHT :: 289.46

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 55 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor

REFERENCE :: TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 9,38,1962

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 60 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor

REFERENCE :: TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 9,38,1962

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 18 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor

REFERENCE :: TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 9,38,1962

Related Compounds

dyclonine
dyclonine hcl
Dyclonine HCL
Dyclonine Impurity 2
Dyclonine Impurity 6
Dyclonine Impurity 3
1-(2-Oxo-2-(thiazol-2-yl)ethyl)piperidine-3-carboxylic acid
1-((2-Chloropyrimidin-4-yl)methyl)piperidine-3-carboxylic acid
1-((2-Chlorothiazol-5-yl)methyl)piperidine-3-carboxylic acid
1-(2-Oxo-2-(pyridin-2-yl)ethyl)piperidine-4-carboxylic acid
1-((3-Chloropyrazin-2-yl)methyl)piperidine-4-carboxylic acid
1-((2,4-Dichloropyrimidin-5-yl)methyl)azetidine-3-carboxylic acid
4-(Benzo[d]thiazol-2-yl)piperazine-2-carboxylic acid
(R)-2-((1-(trifluoromethyl)piperidin-3-yl)oxy)acetic acid
2-((1-(Trifluoromethyl)pyrrolidin-3-yl)oxy)acetic acid
1-(5-Nitrobenzo[d]thiazol-2-yl)piperidin-3-ol

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