(8Z,11Z,14Z)-8,11,14-Icosatrien-5-ynoic acid

Names

[ Name ]:
(8Z,11Z,14Z)-8,11,14-Icosatrien-5-ynoic acid

[Synonym ]:
(8Z,11Z,14Z)-Icosa-8,11,14-trien-5-ynoic acid
(8Z,11Z,14Z)-8,11,14-Icosatrien-5-ynoic acid
5,6-dehydroarachidonic acid
8,11,14-Eicosatrien-5-ynoic acid, (8Z,11Z,14Z)-

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
444.7±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₃₀O₂

[ Molecular Weight ]:
302.451

[ Flash Point ]:
212.2±23.4 °C

[ Exact Mass ]:
302.224579

[ PSA ]:
37.30000

[ LogP ]:
6.63

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.507

MSDS

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H319

[ Precautionary Statements ]:
P210-P280-P305 + P351 + P338-P337 + P313-P403 + P235

[ Risk Phrases ]:
11-16

[ Safety Phrases ]:
16

[ RIDADR ]:
UN 1170 3/PG 2

Precursor & DownStream

Precursor

methyl (8Z,11Z,14Z)-icosa-8,11,14-trien-5-ynoate
1-heptynyl lithium
3-iodo-1,2-octadiene
(1Z,4Z)-1-iodotrideca-1,4-dien-7-yne
1-iodotrideca-1,4,7-triene
methyl 4-(3-tetradeca-2,5,8-trienyloxiren-2-yl)butanoate

DownStream

Articles

Strong suppression by mononuclear leukocytes from human newborns on maternal leukocytes: mediation by prostaglandins.

Clin. Immunol. Immunopathol. 23(3) , 606-15, (1982)

[Synthesis of (8Z,11Z,14Z)-eicosatrien-5-ynoic (5,6-dehydroarachidonic) acid and its transformation into [5,6-3H]arachidonic acid and [5,6-3H]prostaglandins E2 and F2 alpha].

Bioorg. Khim. 13(3) , 415-9, (1987)

8Z,11Z,14Z-Eicosatriene-5-ynoic acid and its tritium-labelled analogue, [5,6-3H]arachidonic acid, have been synthesized on the basis of acetylenic compounds. [5,6-3H]Arachidonic acid has been used as ...

An analysis of the relationship between 5-lipoxygenase product generation and the secretion of preformed mediators from mouse bone marrow-derived mast cells.

J. Immunol. 133(2) , 938-45, (1984)

The quantitative relationships between the secretion of a granule-associated mediator, beta-hexosaminidase, and the oxidative metabolism of arachidonic acid by the 5-lipoxygenase pathway were analyzed...

5,6-dehydrokawain
(8Z,11Z,14Z)-8,11,14-heptadecatrienal
Arachidonic acid-alkyne
Ethyl (8Z,11Z,14Z)-8,11,14-icosatrienoate
8,11,14-Eicosatrienoic Acid
(8Z,11Z,14Z)-octadeca-8,11,14-trienoic acid
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
2-Methyl-5-sulfamoylthiophene-3-carboxylic acid
tert-Butyl-DL-alanine
4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide