1,2,4,7,8-Pentachlorodibenzo-p-dioxin

Suppliers

Names

[ CAS No. ]:
58802-08-7

[ Name ]:
1,2,4,7,8-Pentachlorodibenzo-p-dioxin

[Synonym ]:
Dibenzo-p-dioxin,1,2,4,7,8-pentachloro
1,2,4,7,8-P5CDD
1,2,4,7,8-pentachlorodibenzodioxin
1,2,4,7,8-PCDD
1,2,4,7,8-pentachlorooxanthrene

Chemical & Physical Properties

[ Density]:
1.714g/cm3

[ Boiling Point ]:
443.9ºC at 760mmHg

[ Molecular Formula ]:
C12H3Cl5O2

[ Molecular Weight ]:
356.41600

[ Flash Point ]:
171.7ºC

[ Exact Mass ]:
353.85800

[ PSA ]:
18.46000

[ LogP ]:
6.85160

[ Index of Refraction ]:
1.661

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HP3420000
CHEMICAL NAME :
Dibenzo-p-dioxin, 1,2,4,7,8-pentachloro-
CAS REGISTRY NUMBER :
58802-08-7
BEILSTEIN REFERENCE NO. :
1627438
LAST UPDATED :
199710
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C12-H3-Cl5-O2
MOLECULAR WEIGHT :
356.40
WISWESSER LINE NOTATION :
T C666 BO IOJ DG EG GG LG MG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>5 mg/kg
TOXIC EFFECTS :
Endocrine - changes in spleen weight Endocrine - changes in thymus weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 44,335,1978
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
1125 ug/kg
TOXIC EFFECTS :
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 44,335,1978 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,41,1977 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,41,1977 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin
  • potassium,2,4,5-trichlorophenolate
  • potassium 2,3,5,6-tetrachlorophenolate

DownStream

Related Compounds

  • 3-Nitro-1,2,4,7,8-pentachlorodibenzo-p-dioxin
  • 1,2,4,7,8-pentabromodibenzo-p-dioxin
  • 1,2,4,7,9-Pentachlorodibenzo-p-dioxin
  • 1,2,3,7,8-pentachlorodibenzo-p-dioxin
  • 1,2,3,7,8-Pentachlorodibenzo-p-dioxin
  • 1,2,3,4,7-Pentachlorodibenzo-p-dioxin
  • Tert-butyl 4-(5-oxohex-3-en-1-yl)piperazine-1-carboxylate
  • 1-(1-ethenyl-1H-pyrazol-4-yl)-2,2,2-trifluoroethan-1-one
  • tert-butyl N-[4-chloro-2-(3-oxobut-1-en-1-yl)phenyl]carbamate
  • 1-(2-Methoxy-4-nitrophenyl)-2-(methylamino)ethan-1-one
  • 1,1,1-Trifluoro-3-(5-methyl-1,2-oxazol-4-yl)propan-2-one
  • 3-Oxo-1-[2-(propan-2-yl)-1,3-thiazol-4-yl]cyclobutane-1-carbonitrile
  • 1-(1-ethyl-1H-pyrazol-3-yl)-3-oxocyclobutane-1-carbonitrile
  • 1-(3-Chloro-4-nitrophenyl)-2-(methylamino)ethan-1-one
  • Ethyl 4-(3-oxobut-1-en-1-yl)piperidine-1-carboxylate
  • 1,1,1-trifluoro-3-(1H-indazol-7-yl)propan-2-one
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.