Ambruticin

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Names

[ CAS No. ]:
58857-02-6

[ Name ]:
Ambruticin

[Synonym ]:
(8E)-3,7-Anhydro-2,4,8,9-tetradeoxy-9-[(1S,2S,3R)-2-{(1E,3R,4E)-5-[(2R,6R)-6-ethyl-5-methyl-3,6-dihydro-2H-pyran-2-yl]-3-methylhexa-1,4-dien-1-yl}-3-methylcyclopropyl]-L-gluco-non-8-enonic acid
Antibiotic acid S
SMP 78 Acid S
(1S,5S)-1,5-Anhydro-1-(carboxymethyl)-2-deoxy-5-{(E)-2-[(1S,2S,3R)-2-{(1E,3R,4E)-5-[(2R,6R)-6-ethyl-5-methyl-3,6-dihydro-2H-pyran-2-yl]-3-methyl-1,4-hexadien-1-yl}-3-methylcyclopropyl]vinyl}-L-threo-pentitol
5,6-dihydroxypolyangioic acid
L-gluco-Non-8-enonic acid, 3,7-anhydro-2,4,8,9-tetradeoxy-9-[(1S,2S,3R)-2-[(1E,3R,4E)-5-[(2R,6R)-6-ethyl-3,6-dihydro-5-methyl-2H-pyran-2-yl]-3-methyl-1,4-hexadien-1-yl]-3-methylcyclopropyl]-, (8E)-

Chemical & Physical Properties

[ Density]:
1.201g/cm3

[ Boiling Point ]:
611.5ºC at 760 mmHg

[ Molecular Formula ]:
C28H42O6

[ Molecular Weight ]:
474.62900

[ Flash Point ]:
194.8ºC

[ Exact Mass ]:
474.29800

[ PSA ]:
96.22000

[ LogP ]:
4.43110

[ Index of Refraction ]:
1.617

Synthetic Route

Precursor & DownStream

Precursor

  • methyl 5β,6α-dibenzyloxypolyangioate
  • 2H-Pyran-2-carboxaldehyde, 6-ethyl-3,6-dihydro-5-methyl-, (2R,6R)- (9CI)
  • ((2R,6R)-6-ethyl-5-methyl-3,6-dihydro-2H-pyran-2-yl)methanol
  • 2H-Pyran, 2-ethyl-6-ethynyl-5,6-dihydro-3-methyl-, (2R,6R)- (9CI)
  • (2R,6R)-6-ethyl-2-((E)-1-iodoprop-1-en-2-yl)-5-methyl-3,6-dihydro-2H-pyran
  • (2R,6R)-6-ethyl-5-methyl-2-((E)-penta-2,4-dien-2-yl)-3,6-dihydro-2H-pyran

DownStream


Related Compounds

  • Ambruticin VS-4
  • Ambruticin VS-5
  • Ambruticin VS-1
  • Ambruticin sodium salt
  • 3,3-Difluoro-5-methylhexan-1-ol
  • 2-(4-((tert-Butoxycarbonyl)amino)cyclohexyl)propanoic acid
  • 8-Bromo-1,5-dichloroisoquinoline
  • Methyl 3-amino-6-bromo-2-chlorobenzoate
  • Di-tert-butyl(2',4',6'-triisopropyl-5-methoxy-3,4,6-trimethyl-[1,1'-biphenyl]-2-yl)phosphine
  • 2-(5-(3-Chlorophenyl)-1,2,4-oxadiazol-3-yl)acetohydrazide
  • (3R)-3-methyl-1-(3-methylpyridin-4-yl)piperazine
  • Benzyl trans-3-fluoro-4-[(4-nitrobenzyl)oxy]piperidine-1-carboxylate
  • 6beta-(Hydroxymethyl)piperidine-3alpha,5beta-diol
  • 3-Chloro-4-[3-(cyclopropylmethoxy)phenoxy]aniline
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