Xanthurenic acid

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Names

[ CAS No. ]:
59-00-7

[ Name ]:
Xanthurenic acid

[Synonym ]:
4,8-Dihydroxy-2-quinolinecarboxylic acid
EINECS 200-410-1
4,8-dihydroxy-Quinaldic acid
4,8-Dihydroxyquinoline-2-carboxylic acid
2-quinolinecarboxylic acid, 1,4-dihydro-8-hydroxy-4-oxo-
8-hydroxy-4-oxo-1H-quinoline-2-carboxylic acid
Xanthurenate
Xanthurenic acid
MFCD00006754
2-Quinolinecarboxylic acid, 4,8-dihydroxy-

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
514.4±50.0 °C at 760 mmHg

[ Melting Point ]:
297-298 °C (dec.)(lit.)

[ Molecular Formula ]:
C10H7NO4

[ Molecular Weight ]:
205.167

[ Flash Point ]:
264.9±30.1 °C

[ Exact Mass ]:
205.037506

[ PSA ]:
90.65000

[ LogP ]:
2.64

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.779

[ Storage condition ]:
Store at RT

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UZ9275000
CHEMICAL NAME :
Quinaldic acid, 4,8-dihydroxy-
CAS REGISTRY NUMBER :
59-00-7
BEILSTEIN REFERENCE NO. :
0185954
LAST UPDATED :
199709
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C10-H7-N-O4
MOLECULAR WEIGHT :
205.18
WISWESSER LINE NOTATION :
T66 BNJ CVQ EQ JQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Implant
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
160 mg/kg
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Kidney, Ureter, Bladder - tumors
REFERENCE :
ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- Volume(issue)/page/year: 108,924,1963 *** REVIEWS *** TOXICOLOGY REVIEW AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 23,6,1971

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
UZ9275000

Articles

Automated screening of urine samples for carbohydrates, organic and amino acids after treatment with urease.

J. Chromatogr. A. 562(1-2) , 125-38, (1991)

Eighty-five clinical urine samples and nineteen urine samples previously found by other laboratories to suggest genetic metabolic defects were prepared for trimethylsilylation by treatment with urease...

Vitamin B1 deficiency inhibits the increased conversion of tryptophan to nicotinamide in severe food-restricted rats.

Biosci. Biotechnol. Biochem. 79(1) , 103-8, (2015)

The conversion of tryptophan (Trp) → nicotinamide (Nam) is an important pathway for supplying vitamin niacin. We reported the following two phenomena: (1) severe food restriction led to an increase in...

The urinary ratio of 3-hydroxykynurenine/3-hydroxyanthranilic acid is an index to predicting the adverse effects of D-tryptophan in rats.

J. Nutr. Sci. Vitaminol. 60(4) , 261-8, (2014)

The adverse effects of D-tryptophan and the possibility of it being a surrogate index for predicting adverse effects in rats were investigated. Male rats were fed one of several test diets (20% casein...


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Related Compounds

  • Xanthurenic acid-d4
  • Xanthurenic acid 8-O-glucoside
  • xanthurenic acid 8-methyl ether
  • Octanethioic acid S-propyl ester
  • Hexanethioic acid S-decyl ester
  • Thiopropionic acid S-undecyl ester
  • Methyl 2-fluoro-5-[4-[2-(3-pyridinyl)ethynyl]phenyl]-3-pyridinecarboxylate
  • 1-Morpholinocyclopropanecarboxylic acid
  • 1-(2-Methoxy-6-nitrophenyl)ethanone
  • 1-Methyloctahydro-1H-pyrrolo[2,3-c]pyridine
  • 4-[(4-Benzyl-4h-1,2,4-triazol-3-yl)(hydroxy)methyl]benzonitrile
  • Ethyl 1-(morpholin-4-ylmethyl)cyclopropane-1-carboxylate
  • Methyl 1-morpholin-4-ylcyclopropane-1-carboxylate
  • Methyl 3-(4-(4-bromophenyl)piperazin-1-yl)propanoate
  • (1R,2S)-2-(4-fluorophenyl)cyclopentan-1-amine
  • Methyl 4-(4-phenoxyphenyl)-2-pyridinecarboxylate