D-Galactose

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Names

[ CAS No. ]:
59-23-4

[ Name ]:
D-Galactose

[Synonym ]:
BRAIN SUGAR
galactos
EINECS 200-416-4
D-(+)-Galactose
Dextrogalactose
(+)-Galactose
D-Galactose (9CI)
MFCD00871336
Gal
d-galactos
D(+)-Galactose
(+)-aldehydo-D-galactose
Galactose, D-
D(+)-Glactose
aldehydo-D-galactose
Lactoglucose
cerebrose
MaltaseHydrate
Galactose
D-Galactose

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
527.1±50.0 °C at 760 mmHg

[ Melting Point ]:
168-170 °C(lit.)

[ Molecular Formula ]:
C₆H₁₂O₆

[ Molecular Weight ]:
180.156

[ Flash Point ]:
286.7±26.6 °C

[ Exact Mass ]:
180.063385

[ PSA ]:
110.38000

[ LogP ]:
-3.17

[ Vapour Pressure ]:
0.0±3.1 mmHg at 25°C

[ Index of Refraction ]:
1.573

[ Storage condition ]:
Store at RT.

[ Water Solubility ]:
H2O: 100 mg/mL

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LW5490000

CHEMICAL NAME :: Galactose, D-

CAS REGISTRY NUMBER :: 59-23-4

BEILSTEIN REFERENCE NO. :: 1724619

LAST UPDATED :: 199709

DATA ITEMS CITED :: 12

MOLECULAR FORMULA :: C6-H12-O6

MOLECULAR WEIGHT :: 180.18

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 240 gm/kg

SEX/DURATION :: female 11-22 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

REFERENCE :: JOPDAB Journal of Pediatrics. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1932- Volume(issue)/page/year: 70,676,1967

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 188 gm/kg

SEX/DURATION :: female 8-10 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - eye/ear Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

REFERENCE :: ANENAG Annales d'Endocrinologie. (Masson Editeur, 120 Blvd. Saint-Germain, F-25280 Paris Cedex 06, France) V.1- 1939- Volume(issue)/page/year: 20,203,1959

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 440 gm/kg

SEX/DURATION :: female 1-22 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)

REFERENCE :: JOPDAB Journal of Pediatrics. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1932- Volume(issue)/page/year: 67,438,1965

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 475 gm/kg

SEX/DURATION :: female 3-22 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - other postnatal measures or effects

REFERENCE :: SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 214,1145,1981

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 1000 gm/kg

SEX/DURATION :: female 3-22 day(s) after conception lactating female 21 day(s) post-birth

TOXIC EFFECTS :: Reproductive - Effects on Newborn - germ cell effects (in offspring)

REFERENCE :: SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 214,1145,1981

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 1260 gm/kg

SEX/DURATION :: female 1-21 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - abortion Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4 per # born alive)

REFERENCE :: TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 31,29A,1985

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 630 gm/kg

SEX/DURATION :: female 1-21 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - eye/ear

REFERENCE :: TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 33,46C,1986

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 16500 mg/kg

SEX/DURATION :: female 8-12 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - live birth index (measured after birth)

REFERENCE :: TCMUD8 Teratogenesis, Carcinogenesis, and Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1980- Volume(issue)/page/year: 7,7,1987

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 840 gm/kg

SEX/DURATION :: female 14 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Fertility - other measures of fertility

REFERENCE :: FESTAS Fertility and Sterility. (American Fertility Soc., 608 13th Ave. S, Birmingham, AL 35282) V.1- 1950- Volume(issue)/page/year: 49,522,1988 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81790 No. of Facilities: 97 (estimated) No. of Industries: 2 No. of Occupations: 6 No. of Employees: 1707 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81790 No. of Facilities: 148 (estimated) No. of Industries: 1 No. of Occupations: 7 No. of Employees: 2013 (estimated) No. of Female Employees: 1456 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
LW5490000

[ HS Code ]:
29400090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

N-acelyl-D-glucosamine
4-Nitrophenyl β-D-galactopyranoside
N-acetyl-α-D-glucosamine
Hyperoside
Astragalin
2-ACETAMIDO-2-DEOXY-β-D-GLUCOSAMINE
(2R,3S,4S)-2,3,4-tris(benzyloxy)-4-((4R)-2-(4-methoxyphenyl)-1,3-dioxolan-4-yl)butanal
sesuvioside A
sesuvioside C

DownStream

3,4,6-Tri-O-acetyl-D-galactal
Glyceric Acid
Formic Acid
Glycolic acid
Oxalic acid
2,3,4,6-Tetra-O-acetyl-alpha-D-galactopyranosyl bromide
Mucic acid
Gluconic acid
Raffinose
2-(hydroxymethyl)-4-methoxy-8,8-dimethyl-3,7,9-trioxabicyclo[4.3.0]nonan-5-ol

Customs

[ HS Code ]: 29400090

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D-Galactose
D-Galactose
D-Galactose-d
α-D-Galactose
β-D-galactose
α-D-galactose
1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-(N-methyl-1-phenylformamido)acetate
1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 1-[2-(dimethylamino)ethyl]-5-oxopyrrolidine-3-carboxylate
1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 5-oxo-1-(pentan-3-yl)pyrrolidine-3-carboxylate
1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-(4-methoxyphenoxy)propanoate
1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 5-oxothiolane-3-carboxylate
1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-oxo-1,3-oxazolidine-4-carboxylate
1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 1-methyl-1H-imidazole-5-carboxylate
1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 4-methylthiophene-2-carboxylate
1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-methyl-1H-pyrrole-3-carboxylate
1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl (4S)-2-oxo-1,3-oxazolidine-4-carboxylate

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